Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Subcutaneous unfractionated heparin vs low molecular weight heparin

All‐cause mortality (7 days ‐ 3 months) · people aged ≥ 18 years with a diagnosis of new or recurrent VTE

Subcutaneous unfractionated heparin showed no clear difference in all‐cause mortality (7 days ‐ 3 months) compared with low molecular weight heparin (low certainty).

1 finding from 1 review

Subcutaneous unfractionated heparin vs unfractionated heparin

Major bleedingd (3 months) · people aged ≥ 18 years with a diagnosis of new or recurrent VTE

Subcutaneous unfractionated heparin showed no clear difference in major bleedingd (7 days ‐ 12 months) compared with intravenous unfractionated heparin (low certainty).

1 finding from 1 review

Subcutaneous unfractionated heparin vs unfractionated heparin

All‐cause mortality (5 days to 12 months) · people aged ≥ 18 years with a diagnosis of new or recurrent VTE

Subcutaneous unfractionated heparin showed no clear difference in all‐cause mortality (5 days to 12 months) compared with intravenous unfractionated heparin (low certainty).

1 finding from 1 review

INTENSIVE CASE MANAGEMENT vs NON‐INTENSIVE CASE MANAGEMENT

Social functioning 2. Employment status ‐ by medium term ‐ spent > 1 day employed · people with severe mental disorders

It is very uncertain whether intensive Case Management changes social functioning 2. Employment status ‐ by medium term ‐ spent > 1… compared with non‐Intensive Case Management (very low certainty).

1 finding from 1 review

Laparoscopic vs open surgery

Late overall morbidity (after the first 30 postoperative days: within 6 months) · patients with sigmoid diverticulitis

It is very uncertain whether laparoscopic changes late overall morbidity (after the first 30 postoperative days:… compared with open surgery (very low certainty).

1 finding from 1 review

Laparoscopic vs open surgery

Late overall mortality (after the first 30 postoperative days) · patients with sigmoid diverticulitis

It is very uncertain whether laparoscopic changes late overall mortality (after the first 30 postoperative days) compared with open surgery (very low certainty).

1 finding from 1 review