Findings

What do systematic reviews say?

2,121 questions · 2,186 findings · 242 reviews

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No studies found 493 · 22.6%GRADE not reported 158 · 7.2%Very low 600 · 27.4%Low 474 · 21.7%Moderate 364 · 16.7%High 97 · 4.4%

Oral gentamicin vs nalidixic acid

Serious adverse events ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral gentamicin vs nalidixic acid

Other adverse events ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sulphonamides vs tetracycline

Diarrhoea · patients with Shigella dysentery

It is very uncertain whether sulphonamides changes diarrhoea at compared with tetracycline (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 7.68 [0.46, 128.12]
1 study · 60 participants
Very low

Sulphonamides vs tetracycline

Relapse ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sulphonamides vs tetracycline

Serious adverse events ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Sulphonamides vs tetracycline

Other adverse events ‐ not reported · patients with Shigella dysentery

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fluoroquinolones vs beta‐lactams

Diarrhoea · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes diarrhoea on compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 1.03 [0.45, 2.37]
6 studies · 686 participants
Very low

Fluoroquinolones vs beta‐lactams

Relapse · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes relapse ‐ All trials clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 0.91 [0.11, 7.55]
3 studies · 357 participants
Very low

Fluoroquinolones vs beta‐lactams

Serious adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes serious adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 10.9 [0.61, 194.82]
1 study · 221 participants
Very low

Fluoroquinolones vs beta‐lactams

Discontinuation of medication due to adverse events · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes adverse events leading to discontinuation of treatment compared with beta‐lactams (very low certainty).

1 finding from 1 review

Antibiotic therapy for Shigella dysentery 2010 · Cochrane Headline outcomes only
RR 1.02 [0.27, 3.89]
1 study · 127 participants
Very low

Intervention not reported

Spontaneous bacterial peritonitis · Cirrhotic patients with ascites, without gastro‐intestinal bleeding and no current spontaneous bacterial peritonitis

It is very uncertain whether the intervention changes spontaneous bacterial peritonitis (very low certainty).

1 finding from 1 review

Antibiotic prophylaxis for spontaneous bacterial peritonitis in cirrhotic patients with ascites, without… 2009 · Cochrane Headline outcomes only
RR 0.2 [0.11, 0.37]
7 studies · 538 participants
Very low

Intervention not reported

Mortality · Cirrhotic patients with ascites, without gastro‐intestinal bleeding and no current spontaneous bacterial peritonitis

It is very uncertain whether the intervention changes mortality (very low certainty).

1 finding from 1 review

Antibiotic prophylaxis for spontaneous bacterial peritonitis in cirrhotic patients with ascites, without… 2009 · Cochrane Headline outcomes only
RR 0.61 [0.43, 0.87]
7 studies · 538 participants
Very low

Third generation cephalosporins vs conventional therapy

Death · patients treated for acute bacterial meningitis

1 finding from 1 review

Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis 2007 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 1496 participants
GRADE not reported

Third generation cephalosporins vs conventional therapy

Death · patients treated for meningococcal meningitis

1 finding from 1 review

Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis 2007 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 477 participants
GRADE not reported

Third generation cephalosporins vs conventional therapy

Deafness · patients treated for acute bacterial meningitis

1 finding from 1 review

Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis 2007 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 501 participants
GRADE not reported

Third generation cephalosporins vs conventional therapy

Culture positivity 10 to 48 hours start of treatment · patients treated for acute bacterial meningitis

1 finding from 1 review

Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis 2007 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 442 participants
GRADE not reported

Third generation cephalosporins vs conventional therapy

Diarrhoea · patients treated for acute bacterial meningitis

1 finding from 1 review

Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis 2007 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 750 participants
GRADE not reported

Third generation cephalosporins vs conventional therapy

Neutropenia · patients treated for acute bacterial meningitis

1 finding from 1 review

Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis 2007 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 472 participants
GRADE not reported

Third generation cephalosporins vs conventional therapy

Rash · patients treated for acute bacterial meningitis

1 finding from 1 review

Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis 2007 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 533 participants
GRADE not reported

Third generation cephalosporins vs conventional therapy

Treatment failure (either death or deafness) · patients treated for acute bacterial meningitis

1 finding from 1 review

Third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis 2007 · Cochrane Headline outcomes only
no estimate extracted
19 studies · 1496 participants
GRADE not reported