Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,121 questions · 2,186 findings · 242 reviews

No studies found 493 · 22.6%GRADE not reported 158 · 7.2%Very low 600 · 27.4%Low 474 · 21.7%Moderate 364 · 16.7%High 97 · 4.4%

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Fluoroquinolones vs beta‐lactams

Other adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes other adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Fluoroquinolones vs macrolides

Other adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes other adverse events clinical criteria compared with macrolides (very low certainty).

1 finding from 1 review

Cotrimoxazole vs beta‐lactams

Other adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether cotrimoxazole changes other adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review

Cotrimoxazole vs fluoroquinolones

Other adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether cotrimoxazole changes other adverse events clinical criteria compared with fluoroquinolones (norfloxacin) (very low certainty).

1 finding from 1 review