Findings

What do systematic reviews say?

2,908 questions · 3,101 findings · 509 reviews

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No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Paracetamol 500 mg to 650 mg vs placebo

Any adverse event · adults with episodic tension‐type headache

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Paracetamol 500 mg to 650 mg vs placebo

Serious adverse events · adults with episodic tension‐type headache

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Paracetamol 1000 mg vs placebo

Pain‐free at 1 hour · adults with episodic tension‐type headache

2 findings from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate
Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Paracetamol 1000 mg vs placebo

Use of rescue medication · adults with episodic tension‐type headache

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Paracetamol 1000 mg vs placebo

Pain‐free or mild pain at 2 hours · adults with episodic tension‐type headache

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
High

Paracetamol 1000 mg vs placebo

Any adverse event · adults with episodic tension‐type headache

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
High

Paracetamol 1000 mg vs placebo

Serious adverse events · adults with episodic tension‐type headache

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Paracetamol 500 mg to 650 mg vs placebo

Pain‐free at 2 hours · adults with episodic tension‐type headache

The review found no eligible studies for this question.

1 finding from 1 review

Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ketoprofen 25 mg vs placebo

Pain‐free at 2 hours · adults with episodic tension‐type headache

1 finding from 1 review

Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Ketoprofen 25 mg vs placebo

Pain‐free at different time points (1, 4, 24 hours) · adults with episodic tension‐type headache

1 finding from 1 review

Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Ketoprofen 25 mg vs placebo

Pain‐free or mild pain at 2 hours · adults with episodic tension‐type headache

1 finding from 1 review

Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Ketoprofen 25 mg vs placebo

Use of rescue medication · adults with episodic tension‐type headache

1 finding from 1 review

Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Ketoprofen 25 mg vs placebo

Any adverse event · adults with episodic tension‐type headache

1 finding from 1 review

Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Ketoprofen 25 mg vs placebo

Specific adverse events · adults with episodic tension‐type headache

1 finding from 1 review

Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Ketoprofen 25 mg vs placebo

Serious adverse events · adults with episodic tension‐type headache

1 finding from 1 review

Ketoprofen for episodic tension‐type headache in adults 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Decrease in SBP mmHg mean duration 8.8 weeks · People with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of loop diuretics for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 460 participants
Low

Intervention not reported

Decrease in DBP mmHg mean duration 8.8 weeks · People with primary hypertension

1 finding from 1 review

Blood pressure‐lowering efficacy of loop diuretics for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 460 participants
Low

Intervention not reported

Systolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1007 participants
Low

Intervention not reported

Diastolic blood pressure · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1007 participants
Low

Intervention not reported

Heart rate · Adults with primary hypertension

1 finding from 1 review

Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 977 participants
Low