Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Intervention not reported

Number of participants with at least 1 bleeding episode · people with haematological disorders undergoing intensive chemotherapy or stem cell transplantation

It is very uncertain whether the intervention changes number of participants with at least 1 bleeding episode (very low certainty).

1 finding from 1 review

Intervention not reported

Change in Exercise Capacity (6MWD) · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)
1 finding from 1 review

Intervention not reported

Mortality · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

The intervention showed no clear difference in mortality (low certainty).

1 finding from 1 review

Intervention not reported

Improvement in WHO Functional Class · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

The intervention showed no clear difference in improvement in WHO Functional Class (low certainty).

1 finding from 1 review

Intervention not reported

Serious Adverse Events (Participants with one or more event) · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

It is very uncertain whether the intervention changes serious Adverse Events (Participants with one or more event) (very low certainty).

1 finding from 1 review

Paracetamol 500 mg to 650 mg vs placebo

Pain‐free at 1 hour · adults with episodic tension‐type headache

The review found no eligible studies for this question.

2 findings from 1 review