Intervention not reported
Appearance or exacerbation of gastroesophageal reflux episode: clinical test · infants and young children with cystic fibrosis
1 finding from 1 review
Intervention not reported
Appearance or exacerbation of gastroesophageal reflux episodes: pulmonary events · infants and young children with cystic fibrosis
1 finding from 1 review
Intervention not reported
Peripheral oxygen saturation (%) · infants and young children with cystic fibrosis
1 finding from 1 review
Intervention not reported
Number of exacerbations of upper respiratory tract symptoms · infants and young children with cystic fibrosis
The intervention showed no clear difference in number of exacerbations of upper respiratory tract symptoms (moderate certainty).
1 finding from 1 review
Intervention not reported
Number of days on antibiotics for acute exacerbations · infants and young children with cystic fibrosis
The intervention showed no clear difference in number of days on antibiotics for acute exacerbations (moderate certainty).
1 finding from 1 review
Intervention not reported
Chest X‐ray scores · infants and young children with cystic fibrosis
1 finding from 1 review
Intervention not reported
Pulmonary function test (FVC) % predicted · infants and young children with cystic fibrosis
The intervention showed no clear difference in pulmonary function test (FVC) % predicted (moderate certainty).
1 finding from 1 review
Intervention not reported
Outcomes1 · 117 children with homozygous sickle cell (SS) disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Folate concentration Serum folate levels, measured between 6 and 12 months after entry to the study · 117 children with homozygous sickle cell (SS) disease
1 finding from 1 review
Intervention not reported
Haemoglobin concentration Haematological analyses were performed in the 100/115 (87%) children in whom baseline (within 2 months of entry to study) and 1 year (between 10 and 14 months after entry) · 117 children with homozygous sickle cell (SS) disease
1 finding from 1 review
Intervention not reported
Adverse events ‐ acute splenic sequestration Clinical events experienced by children during the 1 year period commencing at entry to the trial · 117 children with homozygous sickle cell (SS) disease
The intervention showed no clear difference in adverse events ‐ acute splenic sequestration Clinical events… (low certainty).
1 finding from 1 review
Intervention not reported
Adverse events ‐ painful episodes Clinical events experienced by children during the 1 year period commencing at entry to the trial · 117 children with homozygous sickle cell (SS) disease
The intervention showed no clear difference in adverse events ‐ painful episodes Clinical events experienced by… (low certainty).
1 finding from 1 review
Intervention not reported
Adverse events ‐ minor Infections Clinical events experienced by children during the 1 year period commencing at entry to the trial · 117 children with homozygous sickle cell (SS) disease
The intervention showed no clear difference in adverse events ‐ minor Infections Clinical events experienced by… (low certainty).
1 finding from 1 review
Intervention not reported
Adverse events ‐ major infections Clinical events experienced by children during the 1 year period commencing at entry to the trial · 117 children with homozygous sickle cell (SS) disease
The intervention showed no clear difference in adverse events ‐ major infections Clinical events experienced by… (low certainty).
1 finding from 1 review
Intervention not reported
Adverse events ‐ dactylitis Clinical events experienced by children during the 1 year period commencing at entry to the trial · 117 children with homozygous sickle cell (SS) disease
The intervention showed no clear difference in adverse events ‐ dactylitis Clinical events experienced by children… (low certainty).
1 finding from 1 review
Major bleeding, requiring transfusion of packed red blood cells · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in major bleeding requiring transfusion of packed red blood cells compared with placebo (placebo solution/mouthwash); GRADE not reported.
1 finding from 1 review
Number of immediate (less than 24 hours) and delayed (24 hours to 10 days) postoperative bleeding episodes requiring intervention · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… led to lower number of immediate and delayed postoperative bleeding episodes… compared with placebo (placebo solution/mouthwash); GRADE not reported.
1 finding from 1 review
Any postoperative complication except bleeding (e.g. wound infection) · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… showed no clear difference in any postoperative complication except bleeding (e.g. wound infection) compared with placebo (placebo solution/mouthwash); GRADE not reported.
1 finding from 1 review
Number of participants with postoperative bleedings requiring intervention · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… probably leads to lower number of participants with postoperative bleedings requiring… compared with placebo (placebo solution/mouthwash) (moderate certainty).
1 finding from 1 review
Amount of postoperative blood loss (mL) · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found