Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Propofol vs sevoflurane

Adverse event ‐ pain, visual analogue scale · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol showed no clear difference in adverse event ‐ pain, visual analogue scale compared with sevoflurane (low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

Acute myocardial infarction · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes acute myocardial infarction compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

Cardiac ischaemia indicated by ECG · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes cardiac ischaemia indicated by ECG compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs no treatment

Adverse effects: headache · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes side effect (headache) compared with no treatment (very low certainty).

1 finding from 1 review

Nitroglycerin vs placebo

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with placebo (very low certainty).

1 finding from 1 review

Nitroglycerin vs placebo

Acute myocardial infarction · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes acute myocardial infarction compared with placebo (very low certainty).

1 finding from 1 review

Textured vs smooth implants

Capsular contracture Number of women with capsular contracture · women having reconstructive breast surgery

It is very uncertain whether textured changes capsular contracture Number of women with capsular contracture compared with smooth implants (very low certainty).

1 finding from 1 review

Anatomical vs round implants

Reintervention Number of women with reintervention · women having reconstructive breast surgery

It is very uncertain whether anatomical changes reintervention Number of women with reintervention compared with round implants (very low certainty).

1 finding from 1 review

Variable‐ vs fixed‐volume implants

Patient satisfaction: correspondence to expectations Number of women reporting correspondence with expectation · women having reconstructive breast surgery

It is very uncertain whether variable‐ changes patient satisfaction: correspondence to expectations Number of women… compared with fixed‐volume implants (very low certainty).

1 finding from 1 review