Oral misoprostol vs vaginal dinoprostone
Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal dinoprostone (low certainty).
- RR 0.49 [0.4, 0.59]11 studies · 9084 participantsLow
Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal dinoprostone (low certainty).
It is very uncertain whether oral misoprostol changes oxytocin augmentation compared with vaginal dinoprostone (very low certainty).
Oral misoprostol probably leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal dinoprostone (moderate certainty).
Oral misoprostol showed no clear difference in apgar score less than seven at five minutes compared with vaginal dinoprostone (low certainty).
Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal dinoprostone (low certainty).
Oral misoprostol showed no clear difference in vaginal birth within 24 hours compared with vaginal dinoprostone (low certainty).
Oral misoprostol probably leads to lower caesarean section compared with vaginal dinoprostone (moderate certainty).
The intervention showed no clear difference in any stroke or operative death (five‐year cumulative) (moderate certainty).
The intervention showed no clear difference in ipsilateral ischaemic stroke, and any operative stroke or death… (moderate certainty).
The intervention showed no clear difference in disabling or fatal ipsilateral ischaemic or operative stroke and… (moderate certainty).
High showed no clear difference in all‐cause mortality – deaths compared with low alpha‐linolenic acid omega‐3 fats (moderate certainty).
High showed no clear difference in cardiovascular mortality – cardiovascular deaths compared with low alpha‐linolenic acid omega‐3 fats (moderate certainty).
High showed no clear difference in cardiovascular events compared with low alpha‐linolenic acid omega‐3 fats (low certainty).
High showed no clear difference in coronary heart disease mortality – CHD deaths compared with low alpha‐linolenic acid omega‐3 fats (moderate certainty).
High showed no clear difference in coronary heart disease events compared with low alpha‐linolenic acid omega‐3 fats (low certainty).
It is very uncertain whether high changes stroke compared with low alpha‐linolenic acid omega‐3 fats (very low certainty).
High probably leads to lower arrhythmias compared with low alpha‐linolenic acid omega‐3 fats (moderate certainty).
The review found no eligible studies for this question.
It is very uncertain whether high changes harms: pulmonary embolus or DVT compared with low alpha‐linolenic acid omega‐3 fats (very low certainty).
The review found no eligible studies for this question.