Final visual acuity between 20/20 and 20/40 at end of treatment; oral corticosteroids · people with traumatic hyphema
Systemic or topical corticosteroids showed no clear difference in final visual acuity between 20/20 and 20/40 at end of treatment;… compared with placebo or control treatment (low certainty).
1 finding from 1 review
Short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after treatment; topical corticosteroids · people with traumatic hyphema
It is very uncertain whether systemic or topical corticosteroids changes short‐term visual acuity between 20/20 and 20/40 ≤ 2 weeks after… compared with placebo or control treatment (very low certainty).
1 finding from 1 review
Final visual acuity between 20/20 and 20/25 at end of treatment; topical corticosteroids · people with traumatic hyphema
Systemic or topical corticosteroids showed no clear difference in final visual acuity between 20/20 and 20/25 at end of treatment;… compared with placebo or control treatment (low certainty).
1 finding from 1 review
Time to resolution of primary hemorrhage · people with traumatic hyphema
2 findings from 1 review
Risk of secondary hemorrhage; oral corticosteroids · people with traumatic hyphema
Systemic or topical corticosteroids may leads to lower risk of secondary hemorrhage; oral corticosteroids compared with placebo or control treatment (low certainty).
1 finding from 1 review
Risk of secondary hemorrhage; topical corticosteroids · people with traumatic hyphema
It is very uncertain whether systemic or topical corticosteroids changes risk of secondary hemorrhage; topical corticosteroids compared with placebo or control treatment (very low certainty).
1 finding from 1 review
Long‐term visual acuity 20/40 or better > 2 months after treatment · people with traumatic hyphema
Systemic aminocaproic acid showed no clear difference in long‐term visual acuity 20/40 or better > 2 months after treatment compared with placebo (low certainty).
1 finding from 1 review
Final visual acuity 20/40 or better at resolution of hyphema · people with traumatic hyphema
Systemic aminocaproic acid showed no clear difference in final visual acuity 20/40 or better at resolution of hyphema compared with placebo (low certainty).
1 finding from 1 review
Time to resolution of primary hemorrhage · people with traumatic hyphema
1 finding from 1 review
Secondary hemorrhage at any time point · people with traumatic hyphema
Systemic aminocaproic acid may leads to lower secondary hemorrhage at any time point compared with placebo (low certainty).
1 finding from 1 review
Adverse event nausea and vomiting (0 to 24 hours) · people with traumatic hyphema
Systemic aminocaproic acid probably leads to higher adverse effects: nausea or vomiting compared with placebo (moderate certainty).
1 finding from 1 review
Short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment · people with traumatic hyphema
Topical aminocaproic acid showed no clear difference in short‐term visual acuity 20/40 or better ≤ 2 weeks after treatment compared with placebo (low certainty).
1 finding from 1 review
Medium‐term visual acuity 20/40 or better > 2 weeks and ≤ 2 months after treatment · people with traumatic hyphema
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Face‐to‐face behavioral intervention vs minimal or no support (Measured 3 to 6 months with CO‐validated prolonged and continuous abstinence, and self‐reported abstinence) · people who use waterpipe
The intervention may leads to higher face‐to‐face behavioral intervention vs minimal or no support… (low certainty).
1 finding from 1 review
RR 2.64 [1.66, 4.2]
851 participants
Low
Intervention not reported
Varenicline plus behavioral intervention vs placebo plus behavioral intervention ‐ (repeated point prevalence abstinence (not even a puff/chew/session in the last 7 days) at each of weeks 5, 12, and 25 (combined), verified by CO cutoff < 10 ppm) · people who use waterpipe
The intervention showed no clear difference in varenicline plus behavioral intervention vs placebo plus behavioral… (low certainty).
1 finding from 1 review
Intervention not reported
Bupropion therapy plus behavioral intervention vs behavioral intervention alone (continuous waterpipe smoking abstinence, defined as an expired CO of 9 ppm or less at the 6‐month postintervention · people who use waterpipe
It is very uncertain whether the intervention changes bupropion therapy plus behavioral intervention vs behavioral… (very low certainty).
1 finding from 1 review
RR 0.77 [0.42, 1.41]
121 participants
Very low
Intervention not reported
Bupropion therapy plus behavioral support versus self‐help (continuous waterpipe smoking abstinence, defined as an expired CO of 9 ppm or less at the 6‐month postintervention · people who use waterpipe
It is very uncertain whether the intervention changes bupropion therapy plus behavioral support versus self‐help… (very low certainty).
1 finding from 1 review
RR 1.94 [0.94, 4]
86 participants
Very low
Death · patients on HD with HCV infection
Standard interferon showed no clear difference in death compared with placebo or control (low certainty).
1 finding from 1 review
Sustained virological response · patients on HD with HCV infection
Pegylated interferon alpha‐2a showed no clear difference in sustained virological response 6 months after stopping treatment compared with standard interferon (low certainty).
1 finding from 1 review
Treatment discontinuation · patients on HD with HCV infection
Pegylated interferon alpha‐2a showed no clear difference in treatment discontinuation compared with standard interferon (low certainty).
1 finding from 1 review