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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,956 questions in 143 reviews · Musculoskeletal
current versionsNo studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Radiographic progression · people with rheumatoid arthritis Tai Chi for rheumatoid arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Short‐term serious adverse events · people with rheumatoid arthritis Tai Chi for rheumatoid arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Long‐term adverse effects or toxicity · people with rheumatoid arthritis Tai Chi for rheumatoid arthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Withdrawals – overall (at 8 to 12 weeks) · people with rheumatoid arthritis Tai Chi for rheumatoid arthritis (2019) · Cochrane | RR 0.4 [0.19, 0.86] | 7 studies · 289 participants | Low |
Tramadol alone vs placebo Outcomesa · osteoarthritis of the hip or knee, or both Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs placebo Number of participants experiencing any adverse event · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 1.91 [1.32, 2.76] | 1 study · 308 participants | Moderate |
Tramadol in combination with acetaminophen vs placebo Number of participants who withdrew due to adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 2.78 [1.5, 5.16] | 2 studies · 614 participants | Low |
Tramadol in combination with acetaminophen vs placebo Number of participants experiencing any serious adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 1 study · 15 participants | Low |
Tramadol alone vs acetaminophen Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs acetaminophen Pain · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 1 study · 20 participants | Very low |
Tramadol alone vs acetaminophen Physical function · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs acetaminophen Number of participants experiencing any adverse event · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs acetaminophen Number of participants who withdrew due to adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 5 [0.27, 92.62] | 1 study · 20 participants | Very low |
Tramadol alone vs acetaminophen Number of participants experiencing any serious adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs NSAIDs Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs placebo Pain · osteoarthritis of the hip or knee, or both Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 8 studies · 3972 participants | Moderate |
Tramadol alone vs NSAIDs Pain · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 3 studies · 952 participants | Moderate |
Tramadol alone vs NSAIDs Physical function · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 3 studies · 952 participants | Low |
Tramadol alone vs NSAIDs Number of participants experiencing any adverse event · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 1.31 [1.03, 1.67] | 3 studies · 128 participants | Moderate |
Tramadol alone vs NSAIDs Number of participants who withdrew due to adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 1.88 [1.27, 2.76] | 2 studies · 929 participants | Low |
Tramadol alone vs NSAIDs Number of participants experiencing any serious adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 0.21 [0.01, 4.34] | 2 studies · 188 participants | Very low |
Tramadol alone vs other opioids Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs other opioids Pain · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 4 studies · 411 participants | Moderate |
Tramadol alone vs other opioids Physical function · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 1.32 [1.04, 1.68] | 1 study · 190 participants | Moderate |
Tramadol alone vs other opioids Number of participants experiencing any adverse event · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 0.99 [0.87, 1.13] | 3 studies · 438 participants | Very low |
Tramadol alone vs other opioids Number of participants who withdrew due to adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 2.26 [1.52, 3.37] | 3 studies · 438 participants | Low |
Tramadol alone vs placebo Physical function · osteoarthritis of the hip or knee, or both Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 5 studies · 2550 participants | Moderate |
Tramadol alone vs other opioids Number of participants experiencing any serious adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 7.42 [0.39, 141] | 4 studies · 495 participants | Very low |
Tramadol in combination with acetaminophen vs NSAIDs Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs NSAIDs Pain · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 2 studies · 226 participants | Moderate |
Tramadol in combination with acetaminophen vs NSAIDs Physical function · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 1 study · 91 participants | Low |
Tramadol in combination with acetaminophen vs NSAIDs Number of participants experiencing any adverse event · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | RR 1.17 [0.87, 1.57] | 1 study · 97 participants | Low |
Tramadol in combination with acetaminophen vs NSAIDs Number of participants who withdrew due to adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs NSAIDs Number of participants experiencing any serious adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 1 study · 15 participants | Low |
Tramadol in combination with acetaminophen vs other opioids Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs other opioids Pain · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 1 study · 130 participants | Low |
Tramadol in combination with acetaminophen vs other opioids Physical function · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs placebo Number of participants experiencing any adverse events · osteoarthritis of the hip or knee, or both Tramadol for osteoarthritis (2019) · Cochrane | RR 1.34 [1.24, 1.46] | 4 studies · 2039 participants | Moderate |
Tramadol in combination with acetaminophen vs other opioids Number of participants experiencing any adverse event · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs other opioids Number of participants who withdrew due to adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs other opioids Number of participants experiencing any serious adverse events · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol alone vs placebo Number of participants who withdrew due to adverse events · osteoarthritis of the hip or knee, or both Tramadol for osteoarthritis (2019) · Cochrane | RR 2.64 [2.17, 3.2] | 9 studies · 4533 participants | Moderate |
Tramadol alone vs placebo Number of participants experiencing any serious adverse events · osteoarthritis of the hip or knee, or both Tramadol for osteoarthritis (2019) · Cochrane | RR 1.78 [1.11, 2.84] | 7 studies · 3612 participants | Low |
Tramadol in combination with acetaminophen vs placebo Outcomesa · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | NR | No studies |
Tramadol in combination with acetaminophen vs placebo Pain · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 2 studies · 614 participants | Moderate |
Tramadol in combination with acetaminophen vs placebo Physical function · osteoarthritis Tramadol for osteoarthritis (2019) · Cochrane | no estimate extracted | 2 studies · 614 participants | Moderate |
Subacromial decompression vs placebo surgery Paina (scale from 0‐10, 0 is no pain) · people with impingement syndrome without full‐thickness rotator cuff tears Subacromial decompression surgery for rotator cuff disease (2019) · Cochrane | no estimate extracted | 2 studies · 284 participants | High |
Subacromial decompression vs exercises Health‐related quality of life (15D; scale from: 0‐1, 1 is perfect health) · people with impingement syndrome without full‐thickness rotator cuff tears Subacromial decompression surgery for rotator cuff disease (2019) · Cochrane | no estimate extracted | 1 study · 116 participants | Low |
Subacromial decompression vs exercises Adverse events · people with impingement syndrome without full‐thickness rotator cuff tears Subacromial decompression surgery for rotator cuff disease (2019) · Cochrane | RR 0.91 [0.31, 2.65] | 2 studies · 406 participants | Moderate |
Subacromial decompression vs exercises Serious adverse events · people with impingement syndrome without full‐thickness rotator cuff tears Subacromial decompression surgery for rotator cuff disease (2019) · Cochrane | no estimate extracted | NR | Moderate |