LDL‐cholesterol · Participants with normal or elevated blood pressure, but otherwise healthy
1 finding from 1 review
White population, hypertensive, SBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy
1 finding from 1 review
White population, hypertensive, DBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy
1 finding from 1 review
Black population, normotensive, SBP mmHg · Black population with normal or elevated blood pressure, but otherwise healthy
1 finding from 1 review
Black population, normotensive, DBP mmHg · Black population with normal or elevated blood pressure, but otherwise healthy
1 finding from 1 review
Black population, hypertensive, SBP mmHg · Black population with normal or elevated blood pressure, but otherwise healthy
1 finding from 1 review
Black population, hypertensive, DBP mmHg · Black population with normal or elevated blood pressure, but otherwise healthy
1 finding from 1 review
Asian population, normotensive, SBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy
1 finding from 1 review
Total mortality · adult patients with hypertension
Lower BP target showed no clear difference in total mortality compared with standard BP target (high certainty).
1 finding from 1 review
RR 0.95 [0.86, 1.05]
Studies not reported
High
Total serious adverse events№ of participants: 18165(6 RCTs) · adult patients with hypertension
Lower BP target showed no clear difference in total serious adverse events№ of participants: 18165(6 RCTs) compared with standard BP target (moderate certainty).
1 finding from 1 review
RR 1.04 [0.99, 1.08]
Studies not reported
Moderate
Myocardial infarction · adult patients with hypertension
Lower BP target may leads to lower myocardial infarction№ of participants: 38,198(8 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.84 [0.73, 0.96]
Studies not reported
Low
Stroke · adult patients with hypertension
Lower BP target showed no clear difference in stroke№ of participants: 37,087(7 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.88 [0.77, 1.01]
Studies not reported
Low
Congestive heart failure · adult patients with hypertension
Lower BP target may leads to lower congestive heart failure№ of participants: 15,859(5 RCTs) compared with standard BP target (low certainty).
1 finding from 1 review
RR 0.75 [0.6, 0.92]
Studies not reported
Low
Other serious adverse events · adult patients with hypertension
Lower BP target may leads to higher other serious adverse events compared with standard BP target (low certainty).
1 finding from 1 review
RR 1.44 [1.32, 1.59]
Studies not reported
Low
24‐h ambulatory systolic BP · hyperuricaemia in people with hypertension
1 finding from 1 review
24‐h ambulatory diastolic BP · hyperuricaemia in people with hypertension
1 finding from 1 review
Systolic blood pressure · hyperuricaemia in people with hypertension
1 finding from 1 review
Diastolic blood pressure · hyperuricaemia in people with hypertension
1 finding from 1 review
Serum UA · hyperuricaemia in people with hypertension
1 finding from 1 review
Withdrawals due to adverse events · hyperuricaemia in people with hypertension
Uric acid‐lowering drug showed no clear difference in adverse events (withdrawals due to side effects) compared with placebo (low certainty).
1 finding from 1 review