Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

253 questions · 256 findings · 57 reviews · Pregnancy and Childbirth

No studies found 22 · 8.6%GRADE not reported 10 · 3.9%Very low 32 · 12.5%Low 95 · 37.1%Moderate 67 · 26.2%High 30 · 11.7%

DCC with immediate neonatal care with cord intact vs ECC

Chronic lung disease · babies born preterm, and their mothers

DCC with immediate neonatal care with cord intact showed no clear difference in chronic lung disease (CLD) ‐ oxygen supplement at 36 weeks… compared with ECC (low certainty).

1 finding from 1 review

DCC with immediate neonatal care with cord intact vs ECC

Maternal blood loss of 500 mL or greater · babies born preterm, and their mothers

DCC with immediate neonatal care with cord intact showed no clear difference in maternal blood loss of 500 mL or greater compared with ECC (low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs UCM

Death of baby (up to discharge) · babies born preterm, and their mothers

DCC with immediate neonatal care after cord clamping showed no clear difference in death of baby (up to discharge) compared with UCM (low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs UCM

Death or neurodevelopmental impairment at age 2 to 3 years · babies born preterm, and their mothers

It is very uncertain whether DCC with immediate neonatal care after cord clamping changes death or neurodevelopmental impairment at age 2 to 3 years compared with UCM (very low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs UCM

Severe intraventricular haemorrhage · babies born preterm, and their mothers

DCC with immediate neonatal care after cord clamping showed no clear difference in severe intraventricular haemorrhage (IVH grades 3, 4) compared with UCM (low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs UCM

Intraventricular haemorrhage · babies born preterm, and their mothers

It is very uncertain whether DCC with immediate neonatal care after cord clamping changes intraventricular haemorrhage (IVH, all grades) compared with UCM (very low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs UCM

Chronic lung disease · babies born preterm, and their mothers

DCC with immediate neonatal care after cord clamping showed no clear difference in chronic lung disease (CLD) ‐ oxygen supplement at 36 weeks… compared with UCM (low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs ECC (subgroup analysis by gestation)

Severe intraventricular haemorrhage · babies born preterm, and their mothers

DCC with immediate neonatal care after cord clamping showed no clear difference in severe intraventricular haemorrhage (IVH grades 3, 4) compared with ECC (subgroup analysis by gestation) (low certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs ECC (subgroup analysis by gestation)

Intraventricular haemorrhage · babies born preterm, and their mothers

DCC with immediate neonatal care after cord clamping leads to lower intraventricular haemorrhage (IVH, all grades) compared with ECC (subgroup analysis by gestation) (high certainty).

1 finding from 1 review

DCC with immediate neonatal care after cord clamping vs ECC (subgroup analysis by gestation)

Periventricular leukomalacia · babies born preterm, and their mothers

DCC with immediate neonatal care after cord clamping showed no clear difference in periventricular leukomalacia (PVL) compared with ECC (subgroup analysis by gestation) (low certainty).

1 finding from 1 review