Findings

What do systematic reviews say?

210 questions · 219 findings · 12 reviews · Schizophrenia

Sort:Best matchNewest Highest certainty Download CSV

No studies found 37 · 16.9%GRADE not reported 16 · 7.3%Very low 60 · 27.4%Low 44 · 20.1%Moderate 53 · 24.2%High 9 · 4.1%

QUETIAPINE vs RISPERIDONE

Quality of life QLS · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 152 participants
Low

QUETIAPINE vs RISPERIDONE

Adverse effects: 1. Sedation · schizophrenia

QUETIAPINE led to higher adverse effects: 1. Sedation compared with RISPERIDONE; GRADE not reported.

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
RR 1.21 [1.06, 1.38]
8 studies · 2226 participants
GRADE not reported

QUETIAPINE vs RISPERIDONE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · schizophrenia

QUETIAPINE probably leads to lower adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (moderate certainty).

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
RR 0.5 [0.36, 0.69]
8 studies · 2163 participants
Moderate

QUETIAPINE vs RISPERIDONE

Adverse effects: 3. Metabolic weight gain ≥7% of total body weight · schizophrenia

QUETIAPINE showed no clear difference in adverse effects: 3. Metabolic weight gain ≥7% of total body weight compared with RISPERIDONE (moderate certainty).

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
RR 0.96 [0.82, 1.14]
9 studies · 2070 participants
Moderate

QUETIAPINE vs ZIPRASIDONE

Mental state · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 198 participants
Low

QUETIAPINE vs ZIPRASIDONE

Mental state: 2. Positive symptoms ‐ average endpoint score PANSS positive subscore · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 198 participants
Low

QUETIAPINE vs ZIPRASIDONE

Mental state: 3. Negative symptoms ‐ average endpoint score PANSS negative subscore · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 198 participants
Low

QUETIAPINE vs ZIPRASIDONE

Quality of life: substantial improvement · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

QUETIAPINE vs ARIPIPRAZOLE

Quality of life: substantial improvement · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

QUETIAPINE vs ZIPRASIDONE

Adverse effects: 1. Sedation · schizophrenia

QUETIAPINE may leads to higher adverse effects: 1. Sedation compared with ZIPRASIDONE (low certainty).

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
RR 1.36 [1.03, 1.81]
2 studies · 754 participants
Low

QUETIAPINE vs ZIPRASIDONE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · schizophrenia

QUETIAPINE may leads to lower adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson… compared with ZIPRASIDONE (low certainty).

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
RR 0.43 [0.2, 0.93]
1 study · 522 participants
Low

QUETIAPINE vs ZIPRASIDONE

Adverse effects: 3. Metabolic weight gain ≥7% of total body weight · schizophrenia

QUETIAPINE probably leads to higher adverse effects: 3. Metabolic weight gain ≥7% of total body weight compared with ZIPRASIDONE (moderate certainty).

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
RR 2.22 [1.35, 3.63]
2 studies · 754 participants
Moderate

QUETIAPINE vs ARIPIPRAZOLE

Adverse effects: 1. Sedation · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

QUETIAPINE vs ARIPIPRAZOLE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · schizophrenia

QUETIAPINE showed no clear difference in adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson… compared with ARIPIPRAZOLE (low certainty).

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
RR 0.67 [0.12, 3.57]
1 study · 40 participants
Low

QUETIAPINE vs ARIPIPRAZOLE

Adverse effects: 3. Metabolic weight gain ≥7% of total body weight · schizophrenia

QUETIAPINE showed no clear difference in adverse effects: 3. Metabolic ‐ weight gain ≥7% of total body weight compared with ARIPIPRAZOLE (low certainty).

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
RR 0.52 [0.1, 2.74]
2 studies · 155 participants
Low

QUETIAPINE vs CLOZAPINE ‐ all data short term

Mental state · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 232 participants
Low

QUETIAPINE vs CLOZAPINE ‐ all data short term

Mental state: 2. Positive symptoms ‐ average endpoint score PANSS positive subscore · schizophrenia

1 finding from 1 review

Quetiapine versus other atypical antipsychotics for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 142 participants
Low

ZOTEPINE vs CLOZAPINE

Mental state: psychopathology Total endpoint data, BPRS (higher score = worse, scale from: 0‐126) · patients with schizophrenia

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

ZOTEPINE vs RISPERIDONE

Behaviour: No clinically important response (as defined by the original studies) · patients with schizophrenia

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

ZOTEPINE vs REMOXIPRIDE

Mental state: psychopathology Total endpoint data, BPRS (higher score = worse, scale from: 0‐126) · patients with schizophrenia

1 finding from 1 review

Zotepine versus other atypical antipsychotics for schizophrenia 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low