Non‐platinum single‐agent may leads to lower overall survival (OS) compared with non‐platinum combination treatment (low certainty).
Non‐platinum single‐agent may leads to lower 1‐Year survival rate (OS1y) compared with non‐platinum combination treatment (low certainty).
Non‐platinum single‐agent may leads to lower progression‐free survival compared with non‐platinum combination treatment (low certainty).
Non‐platinum single‐agent may leads to higher objective response rate (ORR) compared with non‐platinum combination treatment (low certainty).
It is very uncertain whether non‐platinum single‐agent changes grade 3 and 4 hematological adverse events (AE) ‐ anemia compared with non‐platinum combination treatment (very low certainty).
Non‐platinum single‐agent may leads to higher grade 3 and 4 hematological adverse events (AE) ‐ neutropenia compared with non‐platinum combination treatment (low certainty).
It is very uncertain whether non‐platinum single‐agent changes grade 3 and 4 hematological adverse events (AE) ‐ thrombocytopenia compared with non‐platinum combination treatment (very low certainty).
Single‐dose levonorgestrel showed no clear difference in observed number of pregnancies (all women) compared with split‐dose levonorgestrel (moderate certainty).
The review found no eligible studies for this question.
Single‐dose levonorgestrel showed no clear difference in specific side effects ‐ nausea compared with split‐dose levonorgestrel (moderate certainty).
Single‐dose levonorgestrel showed no clear difference in specific side effects ‐ vomiting compared with split‐dose levonorgestrel (moderate certainty).
Single‐dose levonorgestrel showed no clear difference in specific side effects ‐ spotting/bleeding after treatment compared with split‐dose levonorgestrel (moderate certainty).
Single‐dose levonorgestrel leads to lower menses ‐ early compared with split‐dose levonorgestrel (high certainty).
Single‐dose levonorgestrel showed no clear difference in menses ‐ delay compared with split‐dose levonorgestrel (low certainty).
It is very uncertain whether single dose of antibiotics changes abdominal surgical site infection compared with 24 hours of antibiotics (very low certainty).
It is very uncertain whether single dose of antibiotics changes intra‐abdominal infection compared with 24 hours of antibiotics (very low certainty).
It is very uncertain whether single lens distance glasses changes rate of falls compared with usual (multifocal) glasses (very low certainty).