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Evidence found and GRADE certainty

185 questions · 193 findings · 19 reviews · Haematology

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No studies found 47 · 24.4%GRADE not reported 20 · 10.4%Very low 28 · 14.5%Low 66 · 34.2%Moderate 21 · 10.9%High 11 · 5.7%

Prophylactic platelet transfusion vs non prophylactic or therapeutic platelet transfusion

Bleeding: Number of days on which a significant bleeding event occurred3 · People with a haematological disorder

Prophylactic platelet transfusion showed no clear difference in bleeding: Number of days on which a significant bleeding event… compared with non prophylactic or therapeutic platelet transfusion (low certainty).

1 finding from 1 review

Prophylactic platelet transfusion vs non prophylactic or therapeutic platelet transfusion

Mortality: secondary to bleeding · People with a haematological disorder

Prophylactic platelet transfusion showed no clear difference in mortality: Secondary to bleeding compared with non prophylactic or therapeutic platelet transfusion (low certainty).

1 finding from 1 review

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)

Bleeding: Numbers of patients with at least one significant bleeding event · People with a haematological disorder

Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in bleeding: Numbers of patients with at least one significant bleeding… compared with higher transfusion threshold (20,000 or 30,000) (moderate certainty).

1 finding from 1 review

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)

Mortality: secondary to bleeding · People with a haematological disorder

Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in mortality: secondary to bleeding compared with higher transfusion threshold (20,000 or 30,000) (low certainty).

1 finding from 1 review