What do systematic reviews say?

Swim‐up technique vs wash and centrifugation

The review found no eligible studies for this question.

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Swim‐up technique vs wash and centrifugation

It is very uncertain whether swim‐up technique changes multiple pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.49 [0.02, 13.28]
  1 study · 26 participants
  Very low

Acupuncture vs sham

• Acupuncture and acupressure for premenstrual syndrome 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 67 participants
  Low

Acupuncture vs sham

• Acupuncture and acupressure for premenstrual syndrome 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 67 participants
  Low

Acupuncture vs no treatment

• Acupuncture and acupressure for premenstrual syndrome 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 14 participants
  Very low

Metabolomics vs non metabolomics

Metabolomics showed no clear difference in live birth rate or ongoing pregnancy (Delivery of a live fetus after… compared with non metabolomics (low certainty).

• Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
  OR 1.02 [0.77, 1.35]
  4 studies · 924 participants
  Low

Metabolomics vs non metabolomics

Metabolomics showed no clear difference in miscarriage (Loss of pregnancy before 20 completed weeks of gestation) compared with non metabolomics (low certainty).

• Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
  OR 1.18 [0.77, 1.82]
  3 studies · 869 participants
  Low

Metabolomics vs non metabolomics

Metabolomics showed no clear difference in clinical pregnancy (Presence of a fetal heart on ultrasound scan at… compared with non metabolomics (low certainty).

• Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
  OR 1.11 [0.85, 1.45]
  4 studies · 924 participants
  Low

Metabolomics vs non metabolomics

Metabolomics showed no clear difference in multiple pregnancy (presence of more than 1 gestational sac) compared with non metabolomics (low certainty).

• Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
  OR 1.5 [0.7, 3.19]
  2 studies · 180 participants
  Low

Metabolomics vs non metabolomics

It is very uncertain whether metabolomics changes ectopic pregnancy (a pregnancy in which the fetus develops outside… compared with non metabolomics (very low certainty).

• Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies 2018 · Cochrane Headline outcomes only
  OR 3 [0.12, 74.07]
  1 study · 417 participants
  Very low

GnRHa treatment vs other medical therapies before any surgery

• Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 188 participants
  Moderate

GnRHa treatment vs other medical therapies before any surgery

GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).

• Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
  OR 0.71 [0.3, 1.68]
  1 study · 199 participants
  Moderate

GnRHa treatment vs other medical therapies before any surgery

GnRHa treatment showed no clear difference in preoperative bleeding: Reduction in bleeding to PBAC < 75 ulipristal… compared with other medical therapies before any surgery (moderate certainty).

• Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
  OR 0.39 [0.14, 1.06]
  1 study · 203 participants
  Moderate

SPRM vs placebo

• Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 173 participants
  High

SPRM vs placebo

SPRM may leads to higher preoperative bleeding: (PBAC < 75) ulipristal acetate 5 mg compared with placebo (low certainty).

• Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
  OR 41.41 [15.26, 112.38]
  1 study · 143 participants
  Low

SPRM vs placebo

SPRM may leads to higher preoperative bleeding: Reduction in menstrual bleeding (PBAC < 75)… compared with placebo (low certainty).

• Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
  OR 78.83 [24.02, 258.74]
  1 study · 146 participants
  Low

SPRM vs placebo

• Preoperative medical therapy before surgery for uterine fibroids 2017 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 22 participants
  Low

Coasting vs gonadotrophin‐releasing hormone antagonist

Coasting showed no clear difference in clinical Pregnancy compared with gonadotrophin‐releasing hormone antagonist (low certainty).

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  OR 0.74 [0.42, 1.31]
  1 study · 190 participants
  Low

Coasting vs gonadotrophin‐releasing hormone antagonist

It is very uncertain whether coasting changes multiple pregnancy compared with gonadotrophin‐releasing hormone antagonist (very low certainty).

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  OR 0.84 [0.39, 1.8]
  1 study · 98 participants
  Very low

Coasting vs follicle stimulating hormone administration at time of hCG

Coasting showed no clear difference in clinical Pregnancy compared with follicle stimulating hormone administration at time of hCG (low certainty).

• Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome 2017 · Cochrane Headline outcomes only
  OR 0.92 [0.43, 2.01]
  1 study · 102 participants
  Low