Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

277 questions · 281 findings · 52 reviews · Developmental, Psychosocial and Learning Problems

No studies found 54 · 19.2%GRADE not reported 13 · 4.6%Very low 64 · 22.8%Low 71 · 25.3%Moderate 69 · 24.6%High 10 · 3.6%

Intervention not reported

Proportion with an autism spectrum disorder diagnosis at baseline and · children diagnosed with autism spectrum disorder
1 finding from 1 review

Intervention not reported

Social communication at baseline and · children diagnosed with autism spectrum disorder

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Restricted and repetitive behaviours and interests at baseline and · children diagnosed with autism spectrum disorder

The review found no eligible studies for this question.

1 finding from 1 review

Environmental interventions vs no intervention

Adverse events · children (aged 0–6 years)

The review found no eligible studies for this question.

2 findings from 1 review

Environmental interventions vs no intervention

Blood lead levels (continuous)Blood lead level at end of duration Scale: 0–30 · children (aged 0–6 years)
2 findings from 1 review

Rinse‐free hand wash vs control

Absenteeism due to any illness (within the study period) Calculated as: an incident rate per child‐days possible Length of time observed: range = 1 to 11 months · children aged from birth to 14 years old

It is very uncertain whether rinse‐free hand wash changes absenteeism due to any illness (within the study period) Calculated… compared with control (very low certainty).

1 finding from 1 review

Rinse‐free hand wash vs control

Adverse skin reactions (within the study period) Calculated as: number of events Length of time observed: range = 5 to 8 months · children aged from birth to 14 years old

It is very uncertain whether rinse‐free hand wash changes adverse skin reactions (within the study period) Calculated as:… compared with control (very low certainty).

1 finding from 1 review