Osteoporosis with pathological fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 0.985 [0.846, 1.146]
376746 participants
GRADE not reported
OR 1.003 [0.874, 1.151]
376746 participants
GRADE not reported
OR 0.953 [0.813, 1.117]
376746 participants
GRADE not reported
Forearm fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 0.992 [0.945, 1.042]
490889 participants
GRADE not reported
OR 0.994 [0.948, 1.042]
490889 participants
GRADE not reported
OR 0.990 [0.950, 1.032]
490889 participants
GRADE not reported
Lumbar spine and pelvis fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.062 [0.991, 1.137]
490700 participants
GRADE not reported
Osteoporosis with pathological fracture · European-ancestry adults
Genetically predicted periodontitis had no causal effect on osteoporosis with pathological fracture (single-variable MR, OR 1.003).
2 findings from 1 review
Lumbar spine bone mineral density (BMD) · European GWAS participants
The MVMR IVW interval included zero.
1 finding from 1 review
Lumbar spine and pelvis fracture · European-ancestry adults
Genetically predicted periodontitis had no causal effect on fracture of lumbar spine and pelvis (multivariable MR, OR 1.060).
2 findings from 1 review
Forearm fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 0.992 [0.950, 1.036]
490889 participants
GRADE not reported
Femoral neck bone mineral density (FN-BMD) · European-ancestry adults
Genetically predicted periodontitis had no causal effect on femoral neck BMD.
1 finding from 1 review
Femur fracture · European-ancestry adults
Genetically predicted periodontitis had no causal effect on fracture of femur (multivariable MR, OR 1.034).
2 findings from 1 review
Osteoporosis · European-ancestry adults
Genetically predicted periodontitis had no causal effect on osteoporosis (multivariable MR, OR 1.000).
2 findings from 1 review
Femur fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.024 [0.960, 1.093]
489106 participants
GRADE not reported
Postmenopausal osteoporosis with pathological fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.012 [0.858, 1.193]
281786 participants
GRADE not reported
Osteoporosis with pathological fracture · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.002 [0.867, 1.158]
376746 participants
GRADE not reported
Bone mineral density in forearm · European-ancestry adults
Genetically predicted periodontitis had no causal effect on forearm BMD.
1 finding from 1 review
Lumbar spine bone mineral density (BMD) · European GWAS participants
The SVMR IVW interval excluded zero.
1 finding from 1 review
Forearm fracture · European-ancestry adults
Genetically predicted periodontitis had no causal effect on fracture of forearm (multivariable MR, OR 0.995).
2 findings from 1 review
Femur fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 1.055 [0.979, 1.136]
489106 participants
GRADE not reported
OR 1.044 [0.983, 1.109]
489106 participants
GRADE not reported
OR 1.063 [0.991, 1.140]
489106 participants
GRADE not reported
Postmenopausal osteoporosis with pathological fracture · European GWAS participants
The SVMR Weighted Median interval included the null.
3 findings from 1 review
OR 0.979 [0.826, 1.159]
281786 participants
GRADE not reported
OR 1.014 [0.872, 1.179]
281786 participants
GRADE not reported
OR 0.934 [0.786, 1.111]
281786 participants
GRADE not reported
Postmenopausal osteoporosis with pathological fracture · Postmenopausal women (European ancestry)
Genetically predicted periodontitis had no causal effect on postmenopausal osteoporosis with pathological fracture (single-variable MR, OR 1.014).
2 findings from 1 review
Osteoporosis · European GWAS participants
The MVMR MR-Egger interval included the null.
1 finding from 1 review
OR 1.005 [0.940, 1.074]
483725 participants
GRADE not reported