Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

286 questions · 318 findings · 37 reviews · Developmental, Psychosocial and Learning Problems

No studies found 53 · 16.7%GRADE not reported 19 · 6%Very low 84 · 26.4%Low 96 · 30.2%Moderate 60 · 18.9%High 6 · 1.9%

Amphetamines vs placebo

ADHD symptom severity: clinician rated · adults with ADHD (available evidence for participants aged between 25 to 53 years old)
3 findings from 1 review

Amphetamines vs placebo

ADHD symptom severity: patient rated · adults with ADHD (available evidence for participants aged between 25 to 53 years old)
3 findings from 1 review

Methylphenidate vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Conners' Abbreviated Teacher Rating Scale, Conners' Abbreviated Parent Rating Scale, IOWA Conners' Teacher Rating Scale, Conners' Continuous Performance Task, Child Behaviour Ch... · children with ADHD and comorbid tic disorders
1 finding from 1 review

Methylphenidate vs placebo

Tic severity Measured by standardized rating scales: Yale Global Tic Severity Scale, Tourette Syndrome Severity Scale, Global Tic Rating Scale, Tic Symptom Self‐Report, Hopkins Motor/Vocal Scale · children with ADHD and comorbid tic disorders
1 finding from 1 review

Clonidine vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Conners' Abbreviated Teacher Rating Scale, Conners' Abbreviated Parent Rating Scale, IOWA Conners' Teacher Rating Scale, Conners' Continuous Performance Task, Child Behaviour Ch... · children with ADHD and comorbid tic disorders
1 finding from 1 review

Desipramine (antidepressant) vs placebo

ADHD symptom‐related behavior Measured by standardized rating scales: Child Behaviour Checklist, Gordon Diagnostic System, Clinical Evaluation of Language Function, Matching Familial Figures Test, Porteus Maze Test, Restricted Academic Test, ADHD ... · children with ADHD and comorbid tic disorders
1 finding from 1 review

Desipramine (antidepressant) vs placebo

Tic severity Measured by standardized rating scales: Yale Global Tic Severity Scale, Tourette Syndrome Severity Scale, Hopkins Motor/Vocal Scale; ADHD Parent Linear Analogue Scale · children with ADHD and comorbid tic disorders
1 finding from 1 review