Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

218 questions · 223 findings · 14 reviews · Implants and prosthodontics

No studies found 30 · 13.5%GRADE not reported 165 · 74%Very low 22 · 9.9%Low 4 · 1.8%Moderate 2 · 0.9%High 0 · 0%

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in gingival recession (REC) · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in change in gingival recession (REC) compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Er:YAG laser debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Er:YAG laser debridement showed no clear difference in change in probing attachment level (PAL) compared with manual debridement plus chlorhexidine irrigation/gel; GRADE not reported.

1 finding from 1 review

Nanocrystalline hydroxyapatite (Ostim) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Nanocrystalline hydroxyapatite (Ostim) led to lower change in probing pocket depth (PPD) compared with bovine-derived xenograft (Bio-Oss) plus resorbable barrier; GRADE not reported.

1 finding from 1 review

Metronidazole gel 25% (local antibiotic) vs Ultrasonic debridement

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Metronidazole gel 25% (local antibiotic) showed no clear difference in change in probing pocket depth compared with ultrasonic debridement; GRADE not reported.

1 finding from 1 review

Erbium:YAG laser vs Air-abrasive device (Perio-Flow)

Recurrence of peri-implantitis · People with at least one dental implant affected by perimplantitis

Er:YAG laser led to lower recurrence of peri-implantitis compared with air-abrasive device (Perio-Flow); GRADE not reported.

1 finding from 1 review

Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement plus chlorhexidine irrigation/gel

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox)… led to higher change in probing attachment level (PAL) compared with manual debridement with chlorhexidine (no antibiotic); GRADE not reported.

1 finding from 1 review

Adjunctive local antibiotic (8.5% doxycycline hyclate, Atridox) added to manual debridement vs Manual debridement plus chlorhexidine irrigation/gel

Recurrence of peri-implantitis · People with at least one dental implant affected by perimplantitis
1 finding from 1 review

Erbium:YAG laser vs Air-abrasive device (Perio-Flow)

Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis

Er:YAG laser showed no clear difference in change in probing pocket depth compared with air-abrasive device (Perio-Flow); GRADE not reported.

1 finding from 1 review

Nanocrystalline hydroxyapatite (Ostim) vs Bovine-derived xenograft (Bio-Oss) plus resorbable barrier

Change in probing attachment level (PAL) · People with at least one dental implant affected by perimplantitis

Nanocrystalline hydroxyapatite (Ostim) led to lower change in probing attachment level (PAL) compared with bovine-derived xenograft (Bio-Oss) plus resorbable barrier; GRADE not reported.

1 finding from 1 review