Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,062 questions · 1,113 findings · 171 reviews · Headline outcomes only

No studies found 161 · 14.5%GRADE not reported 41 · 3.7%Very low 269 · 24.2%Low 321 · 28.8%Moderate 252 · 22.6%High 69 · 6.2%

IUI in a natural cycle vs TI or expectant management

Multiple pregnancy rate · participants with unexplained subfertility

IUI in a natural cycle showed no clear difference in multiple pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review

Intervention not reported

Adverse events ‐ Multiple pregnancy · women with subfertility

The review found no eligible studies for this question.

1 finding from 1 review