Any reported adverse effects 6‐12 months after initiating the intervention (long term) · bipolar disorder
Lamotrigine showed no clear difference in any reported adverse effects 6‐12 months after initiating the… compared with placebo (moderate certainty).
1 finding from 1 review
Intervention not reported
Suicide (Observation period ‐ pre‐intervention: 119.5 years; postintervention: 92 years) · adults or children of all ethnicities
The intervention may leads to lower suicide (Observation period ‐ pre‐intervention: 119.5 years;… (low certainty).
1 finding from 1 review
IRR 0.09
12 participants
Low
Intervention not reported
Cost‐effectiveness of interventions · adults or children of all ethnicities
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Suicide (Observation period: pre‐intervention 30.5 years; postintervention 13.5 years) · adults or children of all ethnicities
The intervention may leads to lower suicide (Observation period: pre‐intervention 30.5 years;… (low certainty).
1 finding from 1 review
Intervention not reported
Cost‐effectiveness of interventions · adults or children of all ethnicities
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Suicide (Observation period: pre‐intervention 81.5 years; postintervention 71.8 years) · adults or children of all ethnicities
The intervention may leads to lower suicide (Observation period: pre‐intervention 81.5 years;… (low certainty).
1 finding from 1 review
Intervention not reported
Cost‐effectiveness of interventions (the study reviewed suicide data from a bridge and surrounding areas over a 70‐year period, and estimated reductions in mortality due to the barrier over a 20‐year period) · adults or children of all ethnicities
1 finding from 1 review
no estimate extracted
1 study · 1 participants
Low
Intervention not reported
Suicide (Observation period: pre‐intervention 19.5 years; postintervention 6.5 years) · adults or children of all ethnicities
The intervention may leads to lower suicide (Observation period: pre‐intervention 19.5 years;… (low certainty).
1 finding from 1 review
Intervention not reported
Cost‐effectiveness of interventions · adults or children of all ethnicities
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Cost‐effectiveness of interventions · adults or children of all ethnicities
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Suicide (Observation period ‐ pre‐intervention: 89 years; postintervention 78.5 years) · adults or children of all ethnicities
The intervention may leads to lower suicide (Observation period ‐ pre‐intervention: 89 years;… (low certainty).
1 finding from 1 review
Remission
Family therapy may leads to higher remission post‐intervention compared with standard care/treatment (low certainty).
1 finding from 1 review
Intervention not reported
Relapse/recurrence (end of intervention) · people with persistent depressive disorder
The intervention probably leads to lower relapse/recurrence (end of intervention) (moderate certainty).
1 finding from 1 review
Intervention not reported
Dropout due to any reason (end of intervention) · people with persistent depressive disorder
The intervention showed no clear difference in dropout due to any reason (end of intervention) (low certainty).
1 finding from 1 review
Depression symptom level: improvement (intervention endpoint) · adults
Pharmacy‐based management (pharmacist with or without wider team) showed no clear difference in depression symptom level: improvement (intervention endpoint) compared with treatment (moderate certainty).
1 finding from 1 review
Depression symptom level: change from baseline mean depression score (intervention endpoint) · adults
1 finding from 1 review
Acceptability of the intervention (as measured by participants not attending · adults
Pharmacy‐based management (pharmacist with or without wider team) showed no clear difference in acceptability of the intervention (as measured by participants not… compared with treatment (low certainty).
1 finding from 1 review
Depression (lower scores mean less depression) · clinical diagnosis of depression
1 finding from 1 review
Improvement: as reported by youth at postintervention · children and adolescents, 11 to 18 years old, with mental health problems
1 finding from 1 review
Therapeutic alliance: as reported by youth at postintervention · children and adolescents, 11 to 18 years old, with mental health problems
1 finding from 1 review