FVC · children and young adults with CF
It is very uncertain whether summary of findings ‐ Inhaled mannitol plus dornase alfa changes lung function: FVC mL (percentage change from baseline) compared with dornase alfa (very low certainty).
1 finding from 1 review
Lung function: FEF25‐75 mL/s (percentage change from baseline) · children and young adults with CF
It is very uncertain whether summary of findings ‐ Inhaled mannitol plus dornase alfa changes lung function: FEF25-75 mL/s (percentage change from baseline) compared with dornase alfa (very low certainty).
1 finding from 1 review
Adverse events relating to treatment Scale: mild, moderate, severe and total · children and young adults with CF
1 finding from 1 review
FEV1 (% predicted): mean change from baseline · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
1 finding from 1 review
Need for additional IV or oral antibiotics · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Time to next pulmonary exacerbation · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
1 finding from 1 review
Adverse events (moderate) · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
It is very uncertain whether summary of findings: Inhaled antibiotics plus IV antibiotics changes adverse events moderate adverse events experienced during and after… compared with IV antibiotics only (very low certainty).
1 finding from 1 review
Microbiology Emergence of resistant organisms · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
It is very uncertain whether summary of findings: Inhaled antibiotics plus IV antibiotics changes microbiology Emergence of resistant organisms compared with IV antibiotics only (very low certainty).
1 finding from 1 review
Quality of life: number of participants achieving MCID · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
Summary of findings: Inhaled antibiotics plus IV antibiotics showed no clear difference in quality of life: number of participants achieving MCID compared with IV antibiotics only (low certainty).
1 finding from 1 review
Time off school or work · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Linear growth velocity (cm/year) · children up to 18 years of age with persistent asthma
Effects of different inhaled corticosteroids on growth in children… may leads to higher linear growth velocity (cm/year) compared with beclomethasone (low certainty).
1 finding from 1 review
Linear growth velocity (cm/year) · children up to 18 years of age with persistent asthma
It is very uncertain whether effects of different inhaled corticosteroids on growth in children… changes linear growth velocity (cm/year) compared with budesonide (very low certainty).
1 finding from 1 review
Change in height · children up to 18 years of age with persistent asthma
Effects of different inhaled corticosteroids on growth in children… probably leads to higher change in height (cm) over a period of time compared with budesonide (moderate certainty).
1 finding from 1 review
Need for nasal continuous positive airway pressure · patients with the management of transient tachypnea of the newborn
It is very uncertain whether inhaled corticosteroids changes need for nasal continuous positive airway pressure compared with no treatment or placebo (very low certainty).
1 finding from 1 review
Need for mechanical ventilation · patients with the management of transient tachypnea of the newborn
It is very uncertain whether inhaled corticosteroids changes need for mechanical ventilation compared with no treatment or placebo (very low certainty).
1 finding from 1 review
Length of hospital stay · patients with the management of transient tachypnea of the newborn
1 finding from 1 review
Duration of tachypnoea · patients with the management of transient tachypnea of the newborn
1 finding from 1 review
Persistent pulmonary hypertension · patients with the management of transient tachypnea of the newborn
1 finding from 1 review
Hyperglycaemia · patients with the management of transient tachypnea of the newborn
1 finding from 1 review
Gastrointestinal bleed · patients with the management of transient tachypnea of the newborn
1 finding from 1 review