Summary of findings: low‐dose vs high‐dose PERT
- Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 146 participantsVery low
The review found no eligible studies for this question.
It is very uncertain whether standard‐dose adrenaline (SDA) changes survival to hospital discharge compared with high‐dose adrenaline (HDA) (very low certainty).
It is very uncertain whether standard‐dose adrenaline (SDA) changes survival to hospital admission compared with high‐dose adrenaline (HDA) (very low certainty).
It is very uncertain whether standard‐dose adrenaline (SDA) changes favourable neurological outcomes compared with high‐dose adrenaline (HDA) (very low certainty).
It is very uncertain whether standard‐dose adrenaline (SDA) changes return of spontaneous circulation compared with high‐dose adrenaline (HDA) (very low certainty).
The review found no eligible studies for this question.
Combined spinal‐epidural showed no clear difference in number of women requiring a repeat regional block or a general… compared with high‐dose spinal (low certainty).
It is very uncertain whether combined spinal‐epidural changes number of women requiring supplemental intra‐operative analgesia at… compared with high‐dose spinal (very low certainty).
It is very uncertain whether combined spinal‐epidural changes number of women requiring intra‐operative conversion to general… compared with high‐dose spinal (very low certainty).
It is very uncertain whether combined spinal‐epidural changes number of women satisfied with anaesthesia compared with high‐dose spinal (very low certainty).
Low‐dose opioid‐based GA showed no clear difference in mortality ‐ Death at any time after surgery compared with high‐dose opioid‐based GA (low certainty).
Low‐dose opioid‐based GA showed no clear difference in postoperative myocardial infarction compared with high‐dose opioid‐based GA (low certainty).
Low‐dose opioid‐based GA showed no clear difference in postoperative stroke compared with high‐dose opioid‐based GA (low certainty).
Low‐dose opioid‐based GA showed no clear difference in postoperative tracheal reintubation compared with high‐dose opioid‐based GA (low certainty).