Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

382 questions · 384 findings · 98 reviews

No studies found 54 · 14.1%GRADE not reported 37 · 9.6%Very low 116 · 30.2%Low 99 · 25.8%Moderate 60 · 15.6%High 18 · 4.7%

Intervention not reported

Adverse events that result in the discontinuation of treatment · adults and children with confirmed clinical and parasitological P vivax malaria

It is very uncertain whether the intervention changes adverse events that result in the discontinuation of treatment (very low certainty).

1 finding from 1 review

Induction: liposomal amphotericin vs Amphotericin B

Safety outcomes: drug discontinuation · adults with HIV and progressive disseminated histoplasmosis

It is very uncertain whether induction: liposomal amphotericin changes safety outcomes: drug discontinuation compared with amphotericin deoxycholate (very low certainty).

1 finding from 1 review

Intervention not reported

Treatment discontinuation due to adverse event (safety population) · women with metastatic triple‐negative breast cancer (mTNBC)

The intervention probably leads to lower treatment discontinuation due to adverse event (safety population) (moderate certainty).

1 finding from 1 review

Intervention not reported

All‐cause discontinuation · vascular dementia, mild‐to‐moderate severity
1 finding from 1 review
  • Memantine for dementia 2019 · Cochrane Headline outcomes only
    no estimate extracted
    2 studies · 900 participants
    Low

Intervention not reported

All‐cause discontinuation · Alzheimer's disease (AD), moderate‐to‐severe
1 finding from 1 review
  • Memantine for dementia 2019 · Cochrane Headline outcomes only
    no estimate extracted
    17 studies · 5087 participants
    High

Intensive counseling vs usual family planning care

Rate of discontinuation due to menstrual disturbances · Women of reproductive age seeking to avoid pregnancy

Intensive counseling may leads to lower rate of discontinuation due to menstrual disturbances compared with usual family planning care (low certainty).

1 finding from 1 review

Intensive counseling vs usual family planning care

Rate of discontinuation due to all other adverse events · Women of reproductive age seeking to avoid pregnancy

Intensive counseling showed no clear difference in rate of discontinuation due to all other adverse events compared with usual family planning care (low certainty).

1 finding from 1 review

Bright white light therapy vs infrared light therapy

Overall discontinuation ( · All participants were known SAD patients who had been successfully treated with conventional light therapy in previous winters

It is very uncertain whether bright white light therapy changes overall discontinuation ( compared with infrared light therapy (very low certainty).

1 finding from 1 review

Bright white light therapy vs no light therapy

Overall discontinuation ( · All participants were known SAD patients who had been successfully treated with conventional light therapy in previous winters

It is very uncertain whether bright white light therapy changes overall discontinuation ( compared with no light therapy (very low certainty).

1 finding from 1 review

Infrared light therapy vs no light therapy

Overall discontinuation ( · All participants were known SAD patients who had been successfully treated with conventional light therapy in previous winters

It is very uncertain whether infrared light therapy changes overall discontinuation ( compared with no light therapy (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Light therapy vs no light therapy

Overall discontinuation ( · All participants were known SAD patients who had been successfully treated with conventional light therapy in previous winters

It is very uncertain whether light therapy changes overall discontinuation ( compared with no light therapy (very low certainty).

1 finding from 1 review

Mindfulness‐based cognitive therapy (MBCT) vs treatment

Overall discontinuation ( · adults with a history of SAD but without depressive symptoms when treatment started

It is very uncertain whether mindfulness‐based cognitive therapy (MBCT) changes overall discontinuation rate compared with treatment (very low certainty).

1 finding from 1 review