Findings

What do systematic reviews say?

3,696 questions · 3,815 findings · 855 reviews

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No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Donepezil 23 mg/day vs donepezil 10 mg/day

Cognitive function · people with Alzheimer's disease

1 finding from 1 review

Donepezil for dementia due to Alzheimer's disease 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1704 participants
Moderate

10‐day trimethoprim vs 10‐day trimethoprim+sulfamethoxazole

Persistent bacteriuria · children with lower urinary tract infection

It is very uncertain whether 10‐day trimethoprim changes persistent bacteriuria compared with 10‐day trimethoprim+sulfamethoxazole (very low certainty).

1 finding from 1 review

Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
RR 1.93 [0.38, 9.76]
1 study · 59 participants
Very low

10‐day trimethoprim vs 10‐day trimethoprim+sulfamethoxazole

Persistent symptoms · children with lower urinary tract infection

It is very uncertain whether 10‐day trimethoprim changes persistent symptoms compared with 10‐day trimethoprim+sulfamethoxazole (very low certainty).

1 finding from 1 review

Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
RR 4.84 [0.24, 96.66]
1 study · 59 participants
Very low

10‐day trimethoprim vs 10‐day trimethoprim+sulfamethoxazole

Recurrence · children with lower urinary tract infection

It is very uncertain whether 10‐day trimethoprim changes recurrence compared with 10‐day trimethoprim+sulfamethoxazole (very low certainty).

1 finding from 1 review

Antibiotics for treating lower urinary tract infection in children 2012 · Cochrane Headline outcomes only
RR 2.9 [0.12, 68.5]
1 study · 59 participants
Very low

Primaquine five days vs 14 days

Serious adverse events · People with P. vivax malaria1

1 finding from 1 review

Primaquine for preventing relapse in people with Plasmodium vivax malaria treated with chloroquine 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 186 participants
GRADE not reported

Primaquine five days vs 14 days

Other adverse events · People with P. vivax malaria1

1 finding from 1 review

Primaquine for preventing relapse in people with Plasmodium vivax malaria treated with chloroquine 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 186 participants
GRADE not reported

Day‐surgery vs overnight stay surgery

Short term mortality · patients with laparoscopic cholecystectomy.

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Low

Day‐surgery vs overnight stay surgery

Serious adverse events · patients with laparoscopic cholecystectomy.

It is very uncertain whether day‐surgery changes serious adverse events compared with overnight stay surgery (very low certainty).

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
Rate Ratio 3.24 [0.74, 14.09]
4 studies · 391 participants
Very low

Day‐surgery vs overnight stay surgery

Quality of life · patients with laparoscopic cholecystectomy.

It is very uncertain whether day‐surgery changes quality of life compared with overnight stay surgery (very low certainty).

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 333 participants
Very low

Day‐surgery vs overnight stay surgery

Pain · patients with laparoscopic cholecystectomy.

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 175 participants
Very low

Day‐surgery vs overnight stay surgery

Return to normal activities (days) · patients with laparoscopic cholecystectomy.

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 217 participants
Very low

Day‐surgery vs overnight stay surgery

Patient readmissions · patients with laparoscopic cholecystectomy.

It is very uncertain whether day‐surgery changes number of hospital readmissions compared with overnight stay surgery (very low certainty).

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
Rate ratio 1.25 [0.43, 3.63]
5 studies · 464 participants
Very low

Day‐surgery vs overnight stay surgery

Failed discharge · patients with laparoscopic cholecystectomy.

It is very uncertain whether day‐surgery changes failed discharge compared with overnight stay surgery (very low certainty).

1 finding from 1 review

Day‐surgery versus overnight stay surgery for laparoscopic cholecystectomy 2013 · Cochrane Headline outcomes only
RR 0.96 [0.65, 1.41]
5 studies · 419 participants
Very low

Primaquine three days vs 14 days

Serious adverse events · People with P. vivax malaria1

1 finding from 1 review

Primaquine for preventing relapse in people with Plasmodium vivax malaria treated with chloroquine 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 262 participants
GRADE not reported

Primaquine three days vs 14 days

Other adverse events · People with P. vivax malaria1

1 finding from 1 review

Primaquine for preventing relapse in people with Plasmodium vivax malaria treated with chloroquine 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 262 participants
GRADE not reported

Primaquine seven days vs 14 days

Severe adverse events · People with P. vivax malaria1

1 finding from 1 review

Primaquine for preventing relapse in people with Plasmodium vivax malaria treated with chloroquine 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 126 participants
GRADE not reported

Primaquine seven days vs 14 days

Other adverse events · People with P. vivax malaria1

1 finding from 1 review

Primaquine for preventing relapse in people with Plasmodium vivax malaria treated with chloroquine 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 126 participants
GRADE not reported

Day hospitals vs Inpatient

Feasibility and engagement: lost to · patients with acute psychiatric disorders

Day hospital showed no clear difference in feasibility and engagement: lost to compared with inpatient (moderate certainty).

1 finding from 1 review

Day hospital versus admission for acute psychiatric disorders 2011 · Cochrane Headline outcomes only
RR 0.94 [0.82, 1.08]
5 studies · 1694 participants
Moderate

Day hospitals vs Inpatient

Extent of hospital care: 1. duration of index admission · patients with acute psychiatric disorders

1 finding from 1 review

Day hospital versus admission for acute psychiatric disorders 2011 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1582 participants
Moderate

Day hospitals vs Inpatient

Unemployed (at end of study) · patients with acute psychiatric disorders

Day hospital may leads to lower unemployed (at end of study) compared with inpatient (low certainty).

1 finding from 1 review

Day hospital versus admission for acute psychiatric disorders 2011 · Cochrane Headline outcomes only
RR 0.81 [0.67, 0.97]
2 studies · 320 participants
Low