Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,476 questions · 1,535 findings · 101 reviews

No studies found 233 · 15.2%GRADE not reported 332 · 21.6%Very low 209 · 13.6%Low 343 · 22.3%Moderate 279 · 18.2%High 139 · 9.1%

Maintenance chemotherapy vs observation

Progression‐free survival · patients with epithelial ovarian cancer

Maintenance chemotherapy showed no clear difference in 3‐year PFS compared with observation (moderate certainty).

3 findings from 1 review

Maintenance chemotherapy vs maintenance radiotherapy

Progression‐free survival · patients with epithelial ovarian cancer

Maintenance chemotherapy showed no clear difference in 3‐year PFS compared with maintenance radiotherapy (low certainty).

3 findings from 1 review

Summary of findings table (subcomparison 2): second‐line chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Overall survival · palliative participants with esophageal and GE‐junction carcinoma previously treated with chemotherapy

Summary of findings table (subcomparison 2): second‐line… probably leads to lower overall survival compared with control intervention alone (moderate certainty).

1 finding from 1 review

Summary of findings table (subcomparison 2): second‐line chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Progression‐free survival · palliative participants with esophageal and GE‐junction carcinoma previously treated with chemotherapy

Summary of findings table (subcomparison 2): second‐line… may leads to lower progression‐free survival compared with control intervention alone (low certainty).

1 finding from 1 review

Summary of findings table (subcomparison 2): second‐line chemotherapy or targeted therapy agent(s) plus control intervention vs control intervention

Toxicity · palliative participants with esophageal and GE‐junction carcinoma previously treated with chemotherapy

It is very uncertain whether summary of findings table (subcomparison 2): second‐line… changes toxicity compared with control intervention alone (very low certainty).

1 finding from 1 review

Anti‐EGFR antibody plus chemotherapy vs chemotherapy alone

Grade 3 to 4 diarrhoea · treatment of relapsed epithelial ovarian cancer

It is very uncertain whether anti‐EGFR antibody plus chemotherapy changes toxicity: grade 3 or 4 diarrhoea compared with chemotherapy alone (very low certainty).

2 findings from 1 review