Maintenance chemotherapy vs observation: Progression‐free survival
Maintenance chemotherapy showed no clear difference in 3‐year PFS compared with observation (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Maintenance chemotherapy vs observation 3‐year PFS · patients with epithelial ovarian cancer Maintenance chemotherapy showed no clear difference in 3‐year PFS compared with observation (moderate certainty). Maintenance chemotherapy for ovarian cancer (2013) · Cochrane Headline outcomes only | RR 1.07 [0.91, 1.25] | 4 studies · 541 participants | Moderate |
Maintenance chemotherapy vs observation 5‐year PFS · patients with epithelial ovarian cancer Maintenance chemotherapy showed no clear difference in 5‐year PFS compared with observation (moderate certainty). Maintenance chemotherapy for ovarian cancer (2013) · Cochrane Headline outcomes only | RR 1.06 [0.97, 1.17] | 3 studies · 761 participants | Moderate |
Maintenance chemotherapy vs observation 10‐year PFS · patients with epithelial ovarian cancer Maintenance chemotherapy showed no clear difference in 10‐year PFS compared with observation (moderate certainty). Maintenance chemotherapy for ovarian cancer (2013) · Cochrane Headline outcomes only | RR 0.96 [0.65, 1.41] | 2 studies · 219 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Maintenance chemotherapy for ovarian cancer 2013 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.