Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

197 questions · 212 findings · 20 reviews · Acute Respiratory Infections

No studies found 37 · 17.5%GRADE not reported 19 · 9%Very low 25 · 11.8%Low 35 · 16.5%Moderate 67 · 31.6%High 29 · 13.7%

Magnesium sulphate vs placebo

Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured at 0 to 24 hoursafter treatment · children up to 18 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (Wang score; range 0 to 12; higher =… compared with placebo (very low certainty).

1 finding from 1 review

Magnesium sulphate vs placebo

Clinical severity score (CSS) (Wang score; range 0 to 12; higher = poorer outcome) measured 25 to 48 hoursafter treatment · children up to 18 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (Wang score; range 0 to 12; higher =… compared with placebo (very low certainty).

1 finding from 1 review

Nasal prongs vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with acute lower respiratory tract infections

It is very uncertain whether nasal prongs changes treatment failure Failure to achieve adequate oxygenation (SaO2) compared with nasopharyngeal catheter (very low certainty).

1 finding from 1 review

Mask vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

Face mask may leads to lower treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (low certainty).

1 finding from 1 review

Head box vs nasopharyngeal catheter

Treatment failure Failure to achieve adequate oxygenation (SaO2 greater than 60 mmHg) · children with severe acute LRTIs

It is very uncertain whether head box changes treatment failure Failure to achieve adequate oxygenation (SaO2… compared with nasopharyngeal catheter (very low certainty).

1 finding from 1 review