Postoperative complication: persistent oronasal fistula · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)
Artificial bone graft: InFuse (collagen matrix) impregnated with… showed no clear difference in postoperative complication: persistent oronasal fistula compared with traditional iliac crest cancellous bone graft; GRADE not reported.
1 finding from 1 review
Radiographic assessment: three-dimensional CT scan (0 to 3 grading scale) · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)
Artificial bone graft: InFuse (collagen matrix) impregnated with… led to higher radiographic assessment: three-dimensional CT scan (0 to 3 grading… compared with traditional iliac crest cancellous bone graft; GRADE not reported.
1 finding from 1 review
Number of participants discharged on the same day as surgery · Skeletally mature patients with unilateral cleft lip and palate and an alveolar cleft defect (>5 years; mean age 16.1 years)
Artificial bone graft: InFuse (collagen matrix) impregnated with… led to higher number of participants discharged on the same day as surgery compared with traditional iliac crest cancellous bone graft; GRADE not reported.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
Among fluoride-releasing sealants, the reduction in WSL initiation versus no sealant was not statistically significant (RR 0.69); subgroup not separately GRADE-rated.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
Among non-fluoride sealants, WSL initiation was significantly reduced versus no sealant (RR 0.69); subgroup not separately GRADE-rated.
1 finding from 1 review
White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
White spot lesions were also measured by laser fluorescence in 3 sealant-vs-no-sealant studies, but no meta-analysis was possible due to incompatible reporting.
1 finding from 1 review
Initiation of white spot lesions (WSL), visual-tactile assessment · Patients of any age (11-40 years) receiving comprehensive/fixed orthodontic treatment with fixed appliances
The additional use of a sealant probably reduces the initiation of white spot lesions during fixed orthodontic treatment compared with no sealant (RR 0.70), but the certainty of evidence is very low.
1 finding from 1 review
Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition)
3 findings from 1 review
Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition)
3 findings from 1 review
Unacceptability of treatment (dropouts/exclusions during the trial) · Children and adolescents aged 16 years or less
Fluoride gel (topically applied; operator- or self-applied; any… showed no clear difference in unacceptability of treatment (dropouts/exclusions during the trial) compared with placebo or no treatment; GRADE not reported.
3 findings from 1 review
Mucosal irritation / oral soft tissue allergic reaction (signs of sensitivity) · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Proportion of children not remaining caries-free · Children with primary (deciduous) teeth (younger children)
Fluoride gel (topically applied; operator- or self-applied; any… showed no clear difference in proportion of children not remaining caries-free compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Caries increment on primary (deciduous) tooth surfaces (d(e/m)fs), prevented fraction · Children with primary (deciduous) teeth (younger children)
1 finding from 1 review
Staining · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Signs of acute toxicity during gel application (nausea, gagging, vomiting) · Children and adolescents aged 16 years or less
It is very uncertain whether fluoride gel (topically applied; operator- or self-applied; any… changes signs of acute toxicity during gel application (nausea, gagging,… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Proportion developing new caries · Children and adolescents aged 16 years or younger (permanent dentition)
Fluoride gel (topically applied; operator- or self-applied; any… led to lower proportion of children developing new caries compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Caries increment in primary/deciduous teeth: decayed, (extraction indicated/missing) and filled teeth d(e/m)ft (prevented fraction) · Children with primary (deciduous) teeth (younger children)
The review found no eligible studies for this question.
1 finding from 1 review
Proportion of children not remaining caries-free · Children and adolescents aged 16 years or younger (permanent dentition)
Fluoride gel (topically applied; operator- or self-applied; any… showed no clear difference in proportion of children not remaining caries-free compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Dental caries: dmfs increment (primary teeth) · Children and adolescents aged 16 years or less
The review found no eligible studies for this question.
1 finding from 1 review
Proportion developing new caries · Children and adolescents aged 16 years or less
Fluoride mouthrinse (any fluoride agent, concentration, volume,… showed no clear difference in proportion of children developing one or more new caries compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review