Findings

What do systematic reviews say?

6 questions · 6 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 4 · 66.7%Moderate 1 · 16.7%High 0 · 0%

Leaving the study early · adults with panic disorder

Selective serotonin reuptake inhibitors showed no clear difference in total number of dropouts compared with placebo (moderate certainty).

1 finding from 1 review

Antidepressants versus placebo for panic disorder in adults 2018 · Cochrane Headline outcomes only
RR 0.99 [0.9, 1.09]
23 studies · 4302 participants
Moderate

Leaving the study early · adults with panic disorder

It is very uncertain whether SSRIs changes total number of dropouts compared with benzodiazepines (very low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.71 [1.03, 2.84]
1 study · 154 participants
Very low

Leaving the study early · adults with panic disorder

SSRIs showed no clear difference in total number of dropouts compared with MAOIs (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1 [0.07, 14.55]
1 study · 30 participants
Low

Leaving the study early · adults with panic disorder

SSRIs showed no clear difference in total number of dropouts compared with SNRIs (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.11 [0.74, 1.65]
2 studies · 991 participants
Low

Leaving the study early · adults with panic disorder

SSRIs showed no clear difference in total number of dropouts compared with naSSAs (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.5 [0.29, 7.73]
1 study · 30 participants
Low

Leaving the study early · adults with panic disorder

TCAs showed no clear difference in total number of dropouts compared with SSRI (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 0.98 [0.65, 1.48]
7 studies · 928 participants
Low