Antidepressants vs placebo
Antidepressants probably leads to lower total number of dropouts compared with placebo (moderate certainty).
- RR 0.88 [0.81, 0.97]38 studies · 7850 participantsModerate
Antidepressants probably leads to lower total number of dropouts compared with placebo (moderate certainty).
It is very uncertain whether antidepressants changes total number of dropouts compared with benzodiazepines (very low certainty).
Tricyclic antidepressants probably leads to lower total number of dropouts compared with placebo (moderate certainty).
Selective serotonin reuptake inhibitors showed no clear difference in total number of dropouts compared with placebo (moderate certainty).
Serotonin‐norepinephrine reuptake inhibitors showed no clear difference in total number of dropouts compared with placebo (moderate certainty).
It is very uncertain whether SSRIs changes total number of dropouts compared with benzodiazepines (very low certainty).
TCAs showed no clear difference in total number of dropouts compared with SSRI (low certainty).
TCA showed no clear difference in total number of dropouts compared with MAOI (moderate certainty).
SSRIs showed no clear difference in total number of dropouts compared with MAOIs (low certainty).
SSRIs showed no clear difference in total number of dropouts compared with SNRIs (low certainty).
SSRIs showed no clear difference in total number of dropouts compared with naSSAs (low certainty).
It is very uncertain whether TCAs changes total number of dropouts compared with benzodiazepines (very low certainty).