Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 75%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Wound infection · other open traumatic wounds

It is very uncertain whether NPWT 75 mmHg changes wound infection compared with standard care (very low certainty).

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
RR 0.44 [0.17, 1.1]
1 study · 463 participants
Very low

Wound infection · other open traumatic wounds

It is very uncertain whether NPWT 125 mmHg changes wound infection compared with NPWT 75 mmHg (very low certainty).

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
RR 1.04 [0.31, 3.51]
1 study · 251 participants
Very low

Wound infection · open fracture wounds

It is very uncertain whether NPWT 125 mmHg changes wound infection compared with standard care (very low certainty).

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
RR 0.48 [0.2, 1.13]
4 studies · 596 participants
Very low

Wound infection · other open traumatic wounds

NPWT 125 mmHg showed no clear difference in wound infection compared with standard care (low certainty).

1 finding from 1 review

Negative pressure wound therapy for open traumatic wounds 2018 · Cochrane Headline outcomes only
RR 0.61 [0.31, 1.18]
2 studies · 509 participants
Low