What do systematic reviews say?

TENS vs sham TENS

• Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 54 participants
  Very low

TENS vs no treatment

• Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

TENS vs other active intervention

• Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

TENS with exercise vs exercise

• Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

SSRIs or SNRIs vs other antidepressants

SSRIs or SNRIs showed no clear difference in withdrawals due to adverse events compared with other antidepressants (low certainty).

• Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
  OR 1.04 [0.41, 2.6]
  4 studies · 257 participants
  Low

SSRIs or SNRIs vs placebo

It is very uncertain whether SSRIs or SNRIs changes withdrawals due to adverse events compared with placebo (very low certainty).

• Selective serotonin reuptake inhibitors (SSRIs) and serotonin‐norepinephrine reuptake inhibitors (SNRIs) for the… 2015 · Cochrane Headline outcomes only
  OR 3.72 [0.79, 17.53]
  3 studies · 190 participants
  Very low