Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 31 findings · 10 reviews · Gut

No studies found 6 · 19.4%GRADE not reported 0 · 0%Very low 13 · 41.9%Low 8 · 25.8%Moderate 4 · 12.9%High 0 · 0%

Infliximab 5 mg/kg vs infliximab 10 mg/kg

Withdrawals due to adverse events · Patients with active Crohn's disease

The review found no eligible studies for this question.

2 findings from 1 review

Infliximab 5–10 mg/kg vs placebo

Withdrawals due to adverse events · Patients with active Crohn's disease

The review found no eligible studies for this question.

2 findings from 1 review

Adalimumab vs placebo

Withdrawals due to adverse events · Participants with Crohn's disease in remission

Adalimumab probably leads to lower withdrawals due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Withdrawals due to adverse events · Patients with active Crohn's disease

The intervention showed no clear difference in withdrawals due to adverse events (low certainty).

1 finding from 1 review