Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

MTX combination vs MTX monotherapy

Withdrawals due to adverse events · patients with rheumatoid arthritis

It is very uncertain whether MTX combination changes withdrawal due to adverse reactions (Pooled across regimens) number… compared with MTX monotherapy (very low certainty).

1 finding from 1 review

Methotrexate monotherapy versus methotrexate combination therapy with non‐biologic disease modifying anti‐rheumatic… 2010 · Cochrane Headline outcomes only
RR 1.59 [1.2, 2.12]
17 studies · 1624 participants
Very low