What do systematic reviews say?

Elemental formula supplements vs polymeric formula supplements

Elemental formula supplements showed no clear difference in withdrawals due to adverse events compared with polymeric formula supplements (low certainty).

• Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
  RR 9.75 [0.59, 159.93]
  1 study · 33 participants
  Low

Elemental formula supplements vs no supplementation

• Enteral nutrition for maintenance of remission in Crohn's disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 51 participants
  GRADE not reported

Four‐food elimination and amino acid formula vs four‐food elimination diet

It is very uncertain whether four‐food elimination and amino acid formula changes withdrawals due to adverse events at 6 weeks compared with four‐food elimination diet (very low certainty).

• Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
  RR 0.95 [0.06, 14.22]
  1 study · 41 participants
  Very low

Oral 5‐aminosalicylic acid vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

It is very uncertain whether oral 5‐aminosalicylic acid changes withdrawal due to adverse events compared with comparator 5‐aminosalicylic acid formulation (very low certainty).

• Oral 5‐aminosalicylic acid for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
  RR 1.25
  5 studies · 457 participants
  Very low