What do systematic reviews say?

Corticosteroids vs placebo

It is very uncertain whether corticosteroids changes vomiting ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.52 [0.31, 0.87]
  6 studies · 609 participants
  Very low

Antihistamines vs placebo

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 149 participants
  Very low

Anticholinergic medication vs placebo

It is very uncertain whether anticholinergics changes vomiting ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.79 [0.4, 1.54]
  4 studies · 453 participants
  Very low

5‐HT3 antagonists vs placebo

It is very uncertain whether 5‐HT3 antagonists changes vomiting ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.46 [0.29, 0.73]
  11 studies · 1414 participants
  Very low

Sedation vs placebo

Sedatives probably leads to lower vomiting ‐ intraoperative compared with placebo (moderate certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.35 [0.24, 0.52]
  8 studies · 593 participants
  Moderate

Opioid antagonists vs placebo

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Acupuncture or acupressure vs placebo

Acupressure/acupuncture may leads to lower vomiting ‐ intraoperative compared with placebo (low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.52 [0.33, 0.8]
  9 studies · 1221 participants
  Low

Ginger vs placebo

It is very uncertain whether ginger changes vomiting ‐ intraoperative compared with placebo (very low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.62 [0.38, 1]
  2 studies · 331 participants
  Very low

Dopamine antagonists vs placebo

Dopamine antagonists may leads to lower vomiting ‐ intraoperative compared with placebo (low certainty).

• Interventions for preventing nausea and vomiting in women undergoing regional anaesthesia for caesarean section 2021 · Cochrane Headline outcomes only
  RR 0.41 [0.28, 0.6]
  12 studies · 942 participants
  Low