Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 13 findings · 3 reviews · Headline outcomes only

No studies found 2 · 15.4%GRADE not reported 0 · 0%Very low 0 · 0%Low 5 · 38.5%Moderate 6 · 46.2%High 0 · 0%

Antibiotic prophylaxis vs placebo, no treatment or surveillance only

Number of participants with symptomatic UTI · primary VUR

Antibiotic prophylaxis showed no clear difference in symptomatic UTI by 1 to 2 years: antibiotics versus no prophylaxis compared with surveillance or no treatment (low certainty).

2 findings from 1 review

Full‐mouth ultrasonic scaling plus photodynamic therapy vs full‐mouth ultrasonic scaling alone

Resolution or reduction in severity of any other dental complication: systemic infections (measured by number of episodes after treatment for dental complications under antibiotic prophylaxis) · people with thalassaemia (any age)

The review found no eligible studies for this question.

1 finding from 1 review