Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Epilepsy

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Treatment withdrawal · people with drug‐resistant focal epilepsy

Pregabalin showed no clear difference in treatment withdrawal for any reason compared with active comparators (low certainty).

1 finding from 1 review

Pregabalin add‐on for drug‐resistant focal epilepsy 2022 · Cochrane Headline outcomes only
RR 0.93 [0.76, 1.13]
3 studies · 1286 participants
Low

Treatment withdrawal · people with drug‐resistant focal epilepsy

Pregabalin probably leads to higher treatment withdrawal for any reason compared with placebo (moderate certainty).

1 finding from 1 review

Pregabalin add‐on for drug‐resistant focal epilepsy 2022 · Cochrane Headline outcomes only
RR 1.33 [1.1, 1.6]
9 studies · 2663 participants
Moderate