What do systematic reviews say?

Reduction and pharmacotherapy vs reduction alone

It is very uncertain whether reduction and pharmacotherapy changes subgroup: nicotine patch; smoking cessation (≥ 6 month compared with reduction alone (very low certainty).

• Smoking reduction interventions for smoking cessation 2019 · Cochrane Headline outcomes only
  RR 0.34 [0.02, 5.31]
  1 study · 85 participants
  Very low