Beta‐blockers vs calcium channel blockers
Stroke
Beta‐blockers probably leads to higher total stroke compared with calcium‐channel blockers (moderate certainty).
1 finding from 1 review
- RR 1.24 [1.11, 1.4]3 studies · 44167 participantsModerate
Findings
What do systematic reviews say?
6 questions · 6 findings · 3 reviews
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 5 · 83.3%High 0 · 0%
CCBs vs ACE inhibitor
Stroke · patients with hypertension
CCBs may leads to lower stroke compared with ACE inhibitor (low certainty).
1 finding from 1 review
- Calcium channel blockers versus other classes of drugs for hypertension 2022 · Cochrane Headline outcomes onlyRR 0.9 [0.81, 0.99]7 studies · 27999 participantsLow
CCBs vs ARB
Stroke · patients with hypertension
CCBs showed no clear difference in stroke compared with ARB (moderate certainty).
1 finding from 1 review
- Calcium channel blockers versus other classes of drugs for hypertension 2022 · Cochrane Headline outcomes onlyRR 0.89 [0.76, 1]6 studies · 25611 participantsModerate
CCBs vs diuretics
Stroke · patients with hypertension
CCBs showed no clear difference in stroke compared with diuretic (moderate certainty).
1 finding from 1 review
- Calcium channel blockers versus other classes of drugs for hypertension 2022 · Cochrane Headline outcomes onlyRR 0.94 [0.84, 1.05]5 studies · 34072 participantsModerate
CCBs vs beta‐blocker
Stroke · patients with hypertension
CCBs probably leads to lower stroke compared with β‐blocker (moderate certainty).
1 finding from 1 review
- Calcium channel blockers versus other classes of drugs for hypertension 2022 · Cochrane Headline outcomes onlyRR 0.77 [0.67, 0.88]3 studies · 22249 participantsModerate
First‐line thiazides vs calcium channel blockers
Stroke · patients with hypertension
First‐line thiazides showed no clear difference in total stroke Duration: 1 to 5 years compared with first‐line calcium channel blockers (moderate certainty).
1 finding from 1 review
- First‐line diuretics versus other classes of antihypertensive drugs for hypertension 2023 · Cochrane Headline outcomes onlyRR 1.06 [0.95, 1.18]6 studies · 35217 participantsModerate