Findings

What do systematic reviews say?

3 questions · 5 findings · 1 reviews · Oral and maxillofacial surgery

No studies found 0 · 0%GRADE not reported 4 · 80%Very low 0 · 0%Low 1 · 20%Moderate 0 · 0%High 0 · 0%

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

One study found space closure more likely with crowding than spacing (OR 5.9; single study; not GRADE-rated).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Overall
OR 5.9 [1.3, 27.7]
1 study
GRADE not reported

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the mandible, presence of the third molar increases odds of spontaneous space closure (OR 2.28; low certainty).

1 finding from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
OR 2.28 [1.67, 3.09]
4 studies · 467 participants
Low

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

In the maxilla, spontaneous space closure occurred in about 85% of cases (9 studies; prevalence not GRADE-rated).

3 findings from 1 review

Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Maxilla
Prevalence 85.3 [73.7, 92.3]
9 studies · 665 participants
GRADE not reported
Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Mandible
Prevalence 48.1 [34.5, 62.0]
11 studies · 1095 participants
GRADE not reported
Spontaneous space closure after extraction of permanent first molars in children and adolescents: a systematic review… 2024 All outcomes
Until eruption of the permanent second molar (median follow-up 4.0 years) · University clinics and hospitals in 8 countries (children/adolescents <18 years) · Overall (both jaws)
Prevalence 61.6 [50.2, 71.9]
13 studies · 1787 participants
GRADE not reported