Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 2 reviews · Oral and maxillofacial surgery

No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Second molar at Nolla developmental stage 6-7 at extraction vs Second molar at later Nolla stages at extraction

Spontaneous space closure · Children and adolescents after extraction of a mandibular permanent first molar (before eruption of the second molar)

One study found mandibular Nolla stage 6-7 associated with better space closure (OR 55.1; single study; not GRADE-rated).

1 finding from 1 review

Early extraction of a compromised first permanent molar vs Non-extraction (retained first permanent molar) or contralateral non-extraction side

Spontaneous space closure · Children aged 5 to 15 years with a compromised first permanent molar

Early extraction of a compromised first permanent molar is followed by variable spontaneous closure of the post-extraction space (about 45.5% to 85.2% of cases); certainty was not GRADE-rated (Shekelle category III).

1 finding from 1 review