Findings

What do systematic reviews say?

20 questions · 20 findings · 10 reviews · Metabolic and Endocrine Disorders

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No studies found 17 · 85%GRADE not reported 1 · 5%Very low 1 · 5%Low 1 · 5%Moderate 0 · 0%High 0 · 0%

Intervention not reported

Socioeconomic effects · preschool children (aged 0 to 6 years) with overweight or obesity

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Socioeconomic effects · preschool children (aged 0 to 6 years) with overweight or obesity

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: pioglitazone monotherapy vs another pharmacological glucose‐lowering monotherapy

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: pioglitazone monotherapy vs intensive behaviour‐changing intervention

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: pioglitazone monotherapy vs placebo

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: pioglitazone monotherapy vs no intervention

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Pioglitazone for prevention or delay of type 2 diabetes mellitus and its associated complications in people at risk… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Metformin vs diet and exercise or another antidiabetic drug

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Metformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intraoperative neuromonitoring vs visual nerve identification only during thyroidectomy

Socioeconomic effects

The review found no eligible studies for this question.

1 finding from 1 review

Intraoperative neuromonitoring versus visual nerve identification for prevention of recurrent laryngeal nerve injury… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Acarbose vs no intervention

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Alpha‐glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Acarbose vs placebo

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Alpha‐glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Short‐acting insulin analogues vs regular human insulin

Socioeconomic effects

The review found no eligible studies for this question.

1 finding from 1 review

Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2 diabetes… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Diet vs physical activity or standard treatment

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity or both for prevention or delay of type 2 diabetes mellitus and its associated complications… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Physical activity vs usual care

Socioeconomic effects · people at increased risk for developing type 2 diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Diet, physical activity or both for prevention or delay of type 2 diabetes mellitus and its associated complications… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Socioeconomic effects · people at risk for development of T2DM

The review found no eligible studies for this question.

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Socioeconomic effects · people at risk for development of T2DM

The review found no eligible studies for this question.

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Socioeconomic effects · people at risk for the development of type 2 diabetes mellitus

1 finding from 1 review

Insulin secretagogues for prevention or delay of type 2 diabetes mellitus and its associated complications in persons… 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 9306 participants
GRADE not reported

Intervention not reported

Socioeconomic effects · people at risk for the development of type 2 diabetes mellitus

The review found no eligible studies for this question.

1 finding from 1 review

Insulin secretagogues for prevention or delay of type 2 diabetes mellitus and its associated complications in persons… 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Socioeconomic effects · non‐diabetic adults with insulin resistance

The review found no eligible studies for this question.

1 finding from 1 review

Zinc supplementation for the prevention of type 2 diabetes mellitus in adults with insulin resistance 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table for metformin plus intensive diet and exercise vs intensive diet and exercise

Socioeconomic effects Description: direct medical costs per participant · people at increased risk for developing type 2 diabetes

1 finding from 1 review

Metformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 94 participants
Very low

Adverse event outcomes for dietary combined with physical activity interventions vs usual care

Costs (direct costs of interventions) · people at increased risk for developing type 2 diabetes

1 finding from 1 review

Diet, physical activity or both for prevention or delay of type 2 diabetes mellitus and its associated complications… 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 2775 participants
Low