Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Smoking abstinence at longest · people who smoke

Cytisine may leads to higher smoking abstinence at longest compared with nicotine replacement therapy (low certainty).

1 finding from 1 review

Nicotine receptor partial agonists for smoking cessation 2023 · Cochrane Headline outcomes only
RR 1.43 [1.13, 1.8]
1 study · 1310 participants
Low

Smoking abstinence at longest · people who smoke

Cytisine probably leads to higher smoking abstinence at longest compared with placebo or no medication (moderate certainty).

1 finding from 1 review

Nicotine receptor partial agonists for smoking cessation 2023 · Cochrane Headline outcomes only
RR 1.3 [1.15, 1.47]
4 studies · 4623 participants
Moderate

Smoking abstinence at longest · people who smoke

Cytisine showed no clear difference in smoking abstinence at longest compared with varenicline (low certainty).

1 finding from 1 review

Nicotine receptor partial agonists for smoking cessation 2023 · Cochrane Headline outcomes only
RR 1 [0.79, 1.26]
2 studies · 2131 participants
Low