Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 2 · 66.7%Very low 0 · 0%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%

Methotrexate vs placebo

Significant adverse events · people with inclusion body myositis

Methotrexate probably leads to higher significant adverse events compared with placebo (moderate certainty).

1 finding from 1 review