Findings

What do systematic reviews say?

24 questions · 24 findings · 15 reviews

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No studies found 4 · 16.7%GRADE not reported 0 · 0%Very low 8 · 33.3%Low 10 · 41.7%Moderate 1 · 4.2%High 1 · 4.2%

Prophylactic plasma transfusion before surgery/invasive procedures vs no prophylactic plasma transfusion before surgery/invasive procedures (colloid, crystalloid, placebo, or no treatment)

Serious adverse events measured by surgery or procedure‐related complications within 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hyperimmune immunoglobulin from human plasma vs saline placebo

Serious adverse events up to day 28 (data available only as a composite of serious adverse events or death up to day 28) · individuals with moderate or severe COVID‐19

Hyperimmune immunoglobulin from human plasma showed no clear difference in serious adverse events up to day 28 (data available only as a… compared with saline placebo (low certainty).

1 finding from 1 review

Hyperimmune immunoglobulin for people with COVID‐19 2023 · Cochrane Headline outcomes only
RR 0.72 [0.45, 1.14]
Studies not reported
Low

Intervention not reported

Serious adverse events Measured by: proportion of any serious adverse events Average study duration (range): 4.7 months (14 days to 21 months) · children and adolescents aged 18 years and under diagnosed with ADHD

1 finding from 1 review

Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents – assessment of… 2018 · Cochrane Headline outcomes only
no estimate extracted
51 studies · 162422 participants
Very low

Intervention not reported

Non‐serious adverse events Measured by: proportion of any non‐serious adverse events Average study duration (range): 5.99 months (1 day to 41 months) · children and adolescents aged 18 years and under diagnosed with ADHD

1 finding from 1 review

Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents – assessment of… 2018 · Cochrane Headline outcomes only
no estimate extracted
49 studies · 13978 participants
Very low