What do systematic reviews say?

IPV‐OPV vs IPV

IPV‐OPV showed no clear difference in serious adverse events (≥ 1 symptom related to study drug or not)… compared with IPV (low certainty).

• Sequential inactivated (IPV) and live oral (OPV) poliovirus vaccines for preventing poliomyelitis 2019 · Cochrane Headline outcomes only
  RR 0.92 [0.6, 1.43]
  2 studies · 1063 participants
  Low