Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews

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No studies found 1 · 33.3%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%

Sulfasalazine vs placebo

Serious adverse events · Patients with ankylosing spondylitis

Sulfasalazine showed no clear difference in serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Sulfasalazine for ankylosing spondylitis 2014 · Cochrane Headline outcomes only
OR 7.5 [0.15, 378.16]
1 study · 264 participants
Moderate

Oral 5‐aminosalicylic acid vs sulfasalazine

Serious adverse events · Patients with quiescent ulcerative colitis

The review found no eligible studies for this question.

1 finding from 1 review

Oral 5‐aminosalicylic acid for maintenance of remission in ulcerative colitis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Azathioprine or 6‐mercaptopurine vs mesalazine or sulfasalazine

Serious adverse events · maintenance of remission in Crohn's disease

It is very uncertain whether azathioprine or 6‐mercaptopurine changes serious adverse events compared with mesalazine or sulfasalazine (very low certainty).

1 finding from 1 review

Azathioprine or 6‐mercaptopurine for maintenance of remission in Crohn's disease 2015 · Cochrane Headline outcomes only
RR 9.37 [1.84, 47.72]
2 studies · 235 participants
Very low